Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MITF | O75030 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604321 | 1.00 | MAPT (0.61) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL1755267 | 0.93 | L3MBTL1 (0.58) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL16162246 | 0.91 | MEN1 (0.58) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL18998439 | 0.85 | TDP1 (0.56) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL7512700 | 0.85 | MAPT (0.64) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL5217880 | 0.84 | MAPT (0.63) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL7560417 | 0.84 | L3MBTL1 (0.66) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL16162350 | 0.83 | ALDH1A1 (0.55) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL16162796 | 0.83 | ALDH1A1 (0.55) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL13461622 | 0.83 | MEN1 (0.51) | MAPTPOLBNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650286-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |
| US-7108895-B2 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEMICAL CO., LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| EP-1650284-A2 | Liquid crystal composition containing an optical active compound and liquid crystal electro-optical element | Seimi Chemical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-1650285-A2 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | Seimi Chemical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-1650286-A2 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | Seimi Chemical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-20040079922-A1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEMICAL CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1371712-A1 | LIQUID-CRYSTAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND AND LIQUID-CRYSTAL ELECTROOPTIC ELEMENT | Seimi Chemical Co., Ltd. (JP) | 2003-12-17 | — | — | EP | disclosed |