Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | TEK | Q02763 | 3/20 | 0.51 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983245 | 0.83 | MEN1 (0.70) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| Methyl Alcohol SCHEMBL27724944 | 0.82 | MAPT (0.63) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL27745773 | 0.81 | RAB9A (0.67) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL15454599 | 0.81 | MAPT (0.72) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL27724954 | 0.80 | MAPT (0.65) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30161844 | 0.79 | ALDH1A1 (0.76) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2088159 | 0.79 | ALDH1A1 (0.76) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL19445043 | 0.78 | MAPT (0.81) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4604363 | 0.78 | MAPT (0.67) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL28158582 | 0.77 | MAPT (0.68) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910349-A1 | 2-ARYLBENZOTHIAZOLES AND USES THEREOF | 4SC AG (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007009524-A1 | 2-ARYLBENZOTHIAZOLES AND USES THEREOF | 4SC AG (DE) | 2007-01-25 | — | — | WO | disclosed |
| US-20070021446-A1 | 2-arylbenzothiazole analogues and uses thereof | 4SC AG (DE) | 2007-01-25 | — | — | US | disclosed |
| EP-1746096-A1 | 2-Arylbenzothiazole analogues and uses thereof in the treatment of cancer | 4SC AG (DE) | 2007-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021446-A1 | 2-arylbenzothiazole analogues and uses thereof | NR2E1, NR2E3, NR0B2 | ALDH1A1 1173/4885KDM4E 2243/4885MEN1 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.