Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 18/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107856 | 0.79 | ALOX5AP (0.60) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL15264572 | 0.78 | ALOX5AP (0.57) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL9212939 | 0.76 | PTGS1 (0.61) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL2107324 | 0.73 | ALOX5AP (0.81) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL2108615 | 0.73 | ALOX5AP (0.80) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL9529057 | 0.73 | PDE10A (0.48) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL2108478 | 0.72 | ALOX5AP (1.00) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL7141077 | 0.72 | ALOX5AP (0.48) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL9212984 | 0.72 | ALOX5AP (0.51) | ALOX5APALOX5PTGS1PTGS2CYP3A4 | |
| SCHEMBL4604393 | 0.72 | ALOX5AP (0.77) | ALOX5APALOX5PTGS1PTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871908-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFARCTION, STROKE AND PAOD; METHODS OF TREATMENT | Decode Genetics EHF. (IS) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006105439-A2 | SUSCEPTIBILITY GENE FOR MYOCARDIAL INFARCTION, STROKE. AND PAOD; METHODS OF TREATMENT | DECODE GENETICS EHF. (IS) | 2006-10-05 | — | — | WO | disclosed |