Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.70 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.63 |
| ▸ | DVL1 | O14640 | 1/20 | 0.56 |
| ▸ | HNF4A | P41235 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606969 | 0.82 | DVL1 (0.56) | KDM4EPKMLTC4SDVL1DHODH | |
| SCHEMBL10489814 | 0.82 | LTC4S (0.59) | KDM4EPKMLTC4SDVL1HNF4A | |
| SCHEMBL24901279 | 0.81 | KDM4E (0.56) | KDM4EPKMLTC4SDVL1ALDH1A1 | |
| SCHEMBL28966940 | 0.80 | ALDH1A1 (0.60) | KDM4EPKMDVL1DHODHALDH1A1 | |
| SCHEMBL22650196 | 0.79 | PTPN1 (0.66) | KDM4EPKMHNF4AALDH1A1KMT2A | |
| SCHEMBL3781573 | 0.79 | LTC4S (0.58) | KDM4EPKMLTC4SDVL1HNF4A | |
| SCHEMBL2888623 | 0.79 | KDM4E (0.68) | KDM4EPKMLTC4SDVL1HNF4A | |
| SCHEMBL111479 | 0.78 | KMT2A (0.70) | KDM4EALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29543730 | 0.78 | KMT2A (0.70) | KDM4EALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14075194 | 0.78 | DVL1 (0.78) | KDM4EPKMLTC4SDVL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914152-B | New compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB | 2010-06-09 | — | — | CN | disclosed |
| EP-1720825-B1 | ANTHRANILIC ACID DERIVATIVES, METHODS FOR THEIR PREPARATION AND USE AS DHODH INHIBITORS | ACTIVE BIOTECH AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| CN-1914152-A | New compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2007-02-14 | — | — | CN | disclosed |
| EP-1720825-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | Active Biotech AB (SE) | 2006-11-15 | — | — | EP | disclosed |
| US-7074831-B2 | Compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2006-07-11 | — | — | US | disclosed |
| US-20050187297-A1 | New compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2005-08-25 | — | — | US | disclosed |
| WO-2005075410-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187297-A1 | New compounds, methods for their preparation and use thereof | MALT1, TPMT, FUCA1 | KDM4E 2898/4885PKM 2002/4885LTC4S 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.