Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP5 | Q96HI0 | 7/20 | 0.48 |
| ▸ | SENP2 | Q9HC62 | 7/20 | 0.48 |
| ▸ | SENP1 | Q9P0U3 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603993 | 0.93 | SENP5 (0.47) | SENP5SENP2SENP1ALDH1A1CXCR2 | |
| SCHEMBL4603643 | 0.88 | ALDH1A1 (0.46) | SENP5SENP2SENP1ALDH1A1CXCR2 | |
| SCHEMBL4602975 | 0.88 | CXCR2 (0.55) | SENP5SENP2SENP1ALDH1A1NPSR1 | |
| SCHEMBL4604089 | 0.85 | SENP5 (0.47) | SENP5SENP2SENP1ALDH1A1NPSR1 | |
| SCHEMBL4604073 | 0.84 | SENP2 (0.58) | SENP5SENP2SENP1ALDH1A1KDM4E | |
| SCHEMBL4604908 | 0.84 | PPARA (0.48) | SENP5SENP2SENP1ALDH1A1NPSR1 | |
| SCHEMBL4603697 | 0.83 | SENP5 (0.48) | SENP5SENP2SENP1ALDH1A1NPSR1 | |
| SCHEMBL4604994 | 0.83 | PTPN1 (0.53) | SENP5SENP2SENP1ALDH1A1NPSR1 | |
| SCHEMBL4605712 | 0.83 | PPARA (0.47) | SENP5SENP2SENP1ALDH1A1NPSR1 | |
| SCHEMBL4603395 | 0.82 | FFAR1 (0.53) | CXCR2LMNAMAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685122-B1 | BENZOFURANS AND BENZOTHIOPHENES | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |