Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209272 | 0.83 | KDM4E (0.41) | KDM4EFFAR1PTPN11FNTAFNTB | |
| SCHEMBL4219792 | 0.83 | KDM4E (0.41) | KDM4EFFAR1PTPN11FNTAFNTB | |
| SCHEMBL4219912 | 0.81 | ALOX5 (0.39) | KDM4EFFAR1PTPN11FNTAFNTB | |
| SCHEMBL4211976 | 0.79 | MEN1 (0.37) | KDM4EFFAR1PTPN11SMN1; SMN2ALDH1A1 | |
| SCHEMBL4211967 | 0.79 | MEN1 (0.37) | KDM4EFFAR1PTPN11SMN1; SMN2ALDH1A1 | |
| SCHEMBL4990240 | 0.79 | FFAR1 (0.48) | FFAR1PTPN11 | |
| SCHEMBL4216973 | 0.77 | EPHX2 (0.40) | KDM4EFFAR1PTPN11FNTAFNTB | |
| SCHEMBL4209368 | 0.76 | LMNA (0.41) | KDM4EFFAR1PTPN11ALDH1A1 | |
| SCHEMBL4209357 | 0.76 | LMNA (0.41) | KDM4EFFAR1PTPN11ALDH1A1 | |
| SCHEMBL4361055 | 0.70 | KDM4E (0.38) | KDM4EFFAR1PTPN11SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943213-A2 | PPAR MODULATING BIAROMATIC COMPOUNDS | Galderma Research & Development (FR) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007049158-A2 | PPAR MODULATING BIAROMATIC COMPOUNDS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-05-03 | — | — | WO | disclosed |