Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971306 | 0.81 | FFAR1 (0.48) | FFAR1FFAR4PTPN11LMNAL3MBTL1 | |
| SCHEMBL4990245 | 0.80 | FFAR1 (0.43) | FFAR1FFAR4PTPN11LMNAL3MBTL1 | |
| SCHEMBL67387 | 0.80 | HDAC1 (0.39) | FFAR1FFAR4LMNAL3MBTL1RXRA | |
| SCHEMBL4604906 | 0.79 | KDM4E (0.40) | FFAR1PTPN11 | |
| SCHEMBL4968623 | 0.78 | FFAR1 (0.47) | FFAR1FFAR4PTPN11PPARDAKR1B1 | |
| SCHEMBL4219912 | 0.78 | ALOX5 (0.39) | FFAR1PTPN11PPARG | |
| SCHEMBL4211976 | 0.77 | MEN1 (0.37) | FFAR1PTPN11LMNA | |
| SCHEMBL4211967 | 0.77 | MEN1 (0.37) | FFAR1PTPN11LMNA | |
| SCHEMBL69605 | 0.77 | FFAR1 (0.40) | FFAR1LMNAL3MBTL1PPARGPPARD | |
| SCHEMBL4209272 | 0.77 | KDM4E (0.41) | FFAR1PTPN11L3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781274-B1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-11-05 | — | — | EP | disclosed |