Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606077 | 0.83 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1TDP1KDM4EKMT2A | |
| SCHEMBL4605715 | 0.71 | HSP90AA1 (0.49) | ALDH1A1L3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL5306350 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TDP1KDM4EHPGDHSD17B10 | |
| SCHEMBL4606713 | 0.69 | PTGS2 (0.46) | ALDH1A1L3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL4852306 | 0.68 | — | — | |
| SCHEMBL8796668 | 0.65 | PTGS2 (0.57) | ALDH1A1L3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL9868004 | 0.64 | NPC1 (0.47) | ALDH1A1L3MBTL1TDP1KDM4EHPGD | |
| SCHEMBL2096015 | 0.62 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TDP1KDM4EHPGD | |
| 1,2-Dichlorobenzene SCHEMBL2922912 | 0.62 | TSHR (0.62) | ALDH1A1LMNAHSD11B1CYP2A6 | |
| SCHEMBL2095721 | 0.61 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TDP1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1574505-B1 | 1,2,4-THIADIAZOLE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-7361675-B2 | 1,2,4-thiadiazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20060167266-A1 | 1,2,4- thiadiazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1574505-A1 | 1,2,4-THIADIAZOLE COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2005-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167266-A1 | 1,2,4- thiadiazole compounds and use thereof | CBR3, CBR1, NOX3 | ALDH1A1 518/4885L3MBTL1 166/4885TDP1 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.