SCHEMBL46055

SCHEMBL46055

CON1CCC(N)(N(C(=O)Cc2c(C)cc(C)cc2C)C2CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.33
EPHX2 P34913 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL46056 0.97 MEN1 (0.37) MEN1KMT2AALDH1A1EPHX2
SCHEMBL46114 0.85 MEN1 (0.33) MEN1KMT2AALDH1A1EPHX2
SCHEMBL46061 0.84 MEN1 (0.34) MEN1KMT2AEPHX2
SCHEMBL15032130 0.84 MEN1 (0.32) MEN1KMT2A
SCHEMBL12574778 0.83 MEN1 (0.30) MEN1KMT2A
SCHEMBL46049 0.81 MEN1 (0.38) MEN1KMT2AALDH1A1EPHX2L3MBTL1
SCHEMBL15032132 0.81 MEN1 (0.35) MEN1KMT2AALDH1A1EPHX2
SCHEMBL12574771 0.78 ALDH1A1 (0.36) MEN1KMT2AALDH1A1
SCHEMBL46100 0.78 EPHX2 (0.34) MEN1KMT2AALDH1A1EPHX2
SCHEMBL12071750 0.78 KDM4E (0.32) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011151249-A2 METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA SYNGENTA PARTICIPATIONS AG (CH) 2011-12-08 WO disclosed
WO-2010066780-A1 SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-06-17 WO disclosed