Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46055 | 0.97 | MEN1 (0.33) | MEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL46114 | 0.86 | MEN1 (0.33) | MEN1KMT2AEPHX2ALDH1A1MAPK1 | |
| SCHEMBL46049 | 0.85 | MEN1 (0.38) | MEN1KMT2AGAANPSR1EPHX2 | |
| SCHEMBL15032132 | 0.84 | MEN1 (0.35) | MEN1KMT2AGAANPSR1EPHX2 | |
| SCHEMBL12574778 | 0.82 | MEN1 (0.30) | MEN1KMT2AMAPK1 | |
| SCHEMBL46061 | 0.81 | MEN1 (0.34) | MEN1KMT2AGAANPSR1EPHX2 | |
| SCHEMBL15032130 | 0.81 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL12071750 | 0.79 | KDM4E (0.32) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL46100 | 0.79 | EPHX2 (0.34) | MEN1KMT2AEPHX2ALDH1A1MAPK1 | |
| SCHEMBL46380 | 0.79 | POLB (0.40) | MEN1KMT2AGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |