Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46114 | 0.92 | MEN1 (0.33) | EPHX2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL46353 | 0.92 | LMNA (0.32) | ALDH1A1SIGMAR1 | |
| SCHEMBL46375 | 0.89 | NPSR1 (0.31) | EPHX2ALDH1A1POLBFFAR4MEN1 | |
| SCHEMBL12071750 | 0.87 | KDM4E (0.32) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12071745 | 0.85 | EZH2 (0.32) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL46135 | 0.85 | EPHX2 (0.35) | EPHX2KDM4EALDH1A1SIGMAR1POLB | |
| SCHEMBL15032112 | 0.84 | L3MBTL1 (0.35) | EPHX2KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL46054 | 0.83 | L3MBTL1 (0.30) | — | |
| SCHEMBL19139584 | 0.83 | KMT2A (0.34) | EPHX2KDM4EALDH1A1FFAR4MEN1 | |
| SCHEMBL46140 | 0.83 | TSHR (0.32) | ALDH1A1SIGMAR1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |