Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606564 | 0.97 | MAPT (0.52) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4603338 | 0.97 | MAPT (0.52) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4605634 | 0.87 | ALDH1A1 (0.44) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4643633 | 0.86 | MAPT (0.40) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4647176 | 0.86 | MAPT (0.40) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4603990 | 0.84 | ALDH1A1 (0.44) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4603189 | 0.84 | ALDH1A1 (0.44) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4603505 | 0.83 | PKM (0.41) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4603457 | 0.83 | PKM (0.41) | MAPTCA1CA2CA7CA14 | |
| SCHEMBL4605114 | 0.82 | CA2 (0.53) | CA1CA2CA7CA14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139710-B2 | Aliphatic polyester resin compositions, molded articles of aliphatic polyester resin and method of producing same | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2015-09-22 | — | — | US | disclosed |
| EP-1707598-B1 | ALIPHATIC POLYESTER RESIN COMPOSITION, ALIPHATIC POLYESTER RESIN MOLDING AND PROCESS FOR PRODUCING THE ALIPHATIC POLYESTER RESIN MOLDING | TAKEMOTO OIL & FAT CO LTD (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20070270535-A1 | Aliphatic Polyester Resin Compositions, Molded Articles of Aliphatic Polyester Resin and Method of Producing Same | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2007-11-22 | — | — | US | disclosed |
| EP-1707598-A1 | ALIPHATIC POLYESTER RESIN COMPOSITION, ALIPHATIC POLYESTER RESIN MOLDING AND PROCESS FOR PRODUCING THE ALIPHATIC POLYESTER RESIN MOLDING | Takemoto Yushi Kabushiki Kaisha (JP) | 2006-10-04 | — | — | EP | disclosed |