Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607514 | 0.85 | ADRB3 (0.49) | ADRB3ADRB2ADRB1DNM1 | |
| SCHEMBL4605132 | 0.82 | ADRB3 (0.46) | ADRB3ADRB2ADRB1DNM1DRD1 | |
| SCHEMBL4606756 | 0.80 | ADRB3 (0.47) | ADRB3ADRB2ADRB1DNM1 | |
| SCHEMBL2983464 | 0.80 | ADRB3 (0.74) | ADRB3ADRB2ADRB1DNM1 | |
| SCHEMBL4607708 | 0.79 | BCHE (0.46) | ADRB3ADRB2ADRB1DNM1DRD1 | |
| SCHEMBL4606968 | 0.78 | ADRB3 (0.42) | ADRB3ADRB2ADRB1DNM1 | |
| SCHEMBL4607757 | 0.76 | POLB (0.44) | ADRB3ADRB2ADRB1DNM1 | |
| SCHEMBL4607185 | 0.76 | ADRB3 (0.46) | ADRB3ADRB2ADRB1DNM1 | |
| SCHEMBL4608603 | 0.75 | ADRB3 (0.49) | ADRB3ADRB2ADRB1 | |
| SCHEMBL4607629 | 0.74 | KDM4E (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945612-A2 | HETEROCYCLIC COMPOUNDS AS PSTAT3/IL-6 INHIBITORS | Orchid Research Laboratories Limited (IN) | 2008-07-23 | — | — | EP | claimed |
| WO-2007042912-A2 | HETEROCYCLIC COMPOUNDS AS PSTAT3/IL-6 INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-19 | — | — | WO | claimed |