Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46352 | 0.87 | POLB (0.41) | POLBTP53MAPTALDH1A1KDM4E | |
| SCHEMBL15032125 | 0.86 | ALDH1A1 (0.39) | POLBTP53MAPTALDH1A1KDM4E | |
| SCHEMBL46056 | 0.79 | MEN1 (0.37) | POLBALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL46114 | 0.78 | MEN1 (0.33) | POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL46055 | 0.77 | MEN1 (0.33) | ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12574778 | 0.76 | MEN1 (0.30) | KMT2AMEN1 | |
| SCHEMBL12574771 | 0.76 | ALDH1A1 (0.36) | POLBMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL36994 | 0.73 | ALDH1A1 (0.37) | POLBMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL19956388 | 0.73 | ALDH1A1 (0.34) | POLBTP53MAPTALDH1A1KDM4E | |
| SCHEMBL19140076 | 0.72 | ALDH1A1 (0.38) | POLBMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |