Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366746 | 0.94 | PARP1 (0.47) | PARP1SIGMAR1HSD17B1HSD17B2NPC1 | |
| SCHEMBL27493421 | 0.84 | RAB9A (0.40) | PARP1SIGMAR1HSD17B1HSD17B2NPC1 | |
| SCHEMBL28427633 | 0.84 | TSHR (0.58) | SIGMAR1NPC1ALDH1A1RAB9AHTT | |
| SCHEMBL9547526 | 0.83 | NPSR1 (0.54) | PARP1HSD17B1HSD17B2NPC1ALDH1A1 | |
| SCHEMBL2723730 | 0.83 | HSD17B1 (0.39) | PARP1SIGMAR1HSD17B1HSD17B2NPC1 | |
| SCHEMBL25751951 | 0.82 | SIGMAR1 (0.58) | PARP1SIGMAR1HSD17B1HSD17B2LMNA | |
| Hydrochloric Acid SCHEMBL27926140 | 0.81 | SIGMAR1 (0.57) | PARP1SIGMAR1HSD17B1HSD17B2LMNA | |
| SCHEMBL5634132 | 0.81 | PARP1 (0.48) | PARP1SIGMAR1HSD17B1HSD17B2NPC1 | |
| SCHEMBL1118787 | 0.80 | NPC1 (0.46) | PARP1SIGMAR1HSD17B1HSD17B2NPC1 | |
| SCHEMBL5557095 | 0.80 | SIGMAR1 (0.47) | PARP1SIGMAR1HSD17B1HSD17B2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103483224-A | Substituted urea alcoholysis method for synthesizing carbamate compounds | SHANXI COAL CHEM INST | 2014-01-01 | — | — | CN | disclosed |
| EP-1943214-A2 | HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS | Dow Gloval Technologies Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007015852-A2 | HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-1985001286-A1 | A PROCESS FOR THE PREPARATION OF HERBICIDALLY ACTIVE PHENYL CARBAMATES AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME | KEMISK VA^ERK KO^/GE A/S (DK) | 1985-03-28 | — | — | WO | disclosed |
| US-4430505-A | UREA, PRIMARY AMINES, ALCOHOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4388238-A | FROM PRIMARY AMINES, ALCOHOLS, AND CARBONYL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1983-06-14 | — | — | US | disclosed |