Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776542 | 0.84 | CTSV (0.33) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL7778991 | 0.72 | CTSV (0.36) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL20787033 | 0.66 | ALDH1A1 (0.32) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL4607080 | 0.61 | CTSV (0.40) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL7777875 | 0.61 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL7028874 | 0.60 | CTSV (0.38) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL7627326 | 0.60 | CTSV (0.35) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL23005519 | 0.56 | CTSV (0.39) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL12841653 | 0.56 | — | — | |
| SCHEMBL24769790 | 0.55 | APLNR (0.32) | CTSVCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010684-B1 | PROCESS FOR PRODUCING 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE | KYOWA YUKA KK (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-6331653-B1 | Process for producing 3,4-dihydroxy-3-cyclobutene-1,2-dione | KYOWA YUKA CO., LTD. (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-1010684-A1 | PROCESS FOR PRODUCING 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE | Kyowa Yuka Co., Ltd. (JP) | 2000-06-21 | — | — | EP | disclosed |