Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23885336 | 0.85 | HDAC1 (0.54) | TDP1ALDH1A1HDAC1CA12CA1 | |
| SCHEMBL18797052 | 0.83 | KMT2A (0.44) | TDP1ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7659979 | 0.82 | HTT (0.54) | TDP1ALDH1A1CA12CA1CA2 | |
| SCHEMBL7509092 | 0.82 | TDP1 (0.60) | TDP1ALDH1A1HDAC1CA12CA1 | |
| SCHEMBL30442658 | 0.82 | TDP1 (0.60) | TDP1ALDH1A1HDAC1CA12CA1 | |
| SCHEMBL28297598 | 0.82 | SMN1; SMN2 (0.50) | TDP1ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29780101 | 0.82 | SMN1; SMN2 (0.50) | TDP1ALDH1A1SMN1; SMN2MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7516181 | 0.81 | TDP1 (0.58) | TDP1ALDH1A1HDAC1CA12CA1 | |
| SCHEMBL1832506 | 0.79 | ALDH1A1 (0.57) | TDP1ALDH1A1HDAC1CA12CA1 | |
| SCHEMBL2081736 | 0.79 | TDP1 (0.57) | TDP1ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276952-A1 | 4-AMINOPHENYL-THIAZOLE DERIVATIVES AND METHODS OF USE THEREOF | CYTEIR THERAPEUTICS INC (US) | 2025-09-04 | — | — | US | disclosed |
| WO-2023211942-A1 | 4-AMINOPHENYL-THIAZOLE DERIVATIVES AND METHODS OF USE THEREOF | CYTEIR THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023211942-A1 | 4-AMINOPHENYL-THIAZOLE DERIVATIVES AND METHODS OF USE THEREOF | CYTEIR THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | WEIGAND KLAUS | 2008-12-11 | — | — | US | disclosed |
| CN-101296911-A | Arylurea derivatives as modulators of chemokine receptor activity | NOVARTIS AG (CH) | 2008-10-29 | — | — | CN | disclosed |
| EP-1943235-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Novartis AG (CH) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048771-A1 | ARYLUREA DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2007-05-03 | — | — | WO | disclosed |
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306067-A1 | Modulators of Chemokine Receptor Activity | CCR3, CCR1, CCR4 | TDP1 4526/4885ALDH1A1 906/4885HDAC1 732/4885 |
| US-20250276952-A1 | 4-AMINOPHENYL-THIAZOLE DERIVATIVES AND METHODS OF USE THEREOF | ABAT, PYGB, MAPT | TDP1 61/4885ALDH1A1 189/4885HDAC1 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.