Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.37 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | PYGM | P11217 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843231 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL4653458 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL12899847 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL29776749 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL5971391 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL13177330 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL5707581 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL17285835 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL17285836 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL5707577 | 1.00 | PYGB (0.37) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305284-B1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2008-11-12 | — | — | EP | claimed |
| EP-1305284-A4 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2005-08-03 | — | — | EP | claimed |
| EP-1305284-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2003-05-02 | — | — | EP | claimed |
| US-6423867-B1 | FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-07-23 | — | — | US | claimed |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | claimed |
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | claimed |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2002-02-28 | — | — | US | claimed |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERS | 2002-02-28 | — | — | US | claimed |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING | 2002-02-14 | — | — | US | claimed |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-14 | — | — | US | claimed |
| WO-2002010130-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2002-02-07 | — | — | WO | claimed |
| EP-1305284-B1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2008-11-12 | — | — | EP | disclosed |
| EP-1947082-A2 | Oximes or imines of 4-pentulosonic acid methyl esters as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947084-A2 | 2-Pyrrolidones as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1631573-A1 | PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES | INALCO SpA (IT) | 2006-03-08 | — | — | EP | disclosed |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING | 2002-02-14 | — | — | US | disclosed |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-14 | — | — | US | disclosed |
| WO-2002010130-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2002-02-07 | — | — | WO | disclosed |
| US-6121296-A | ADMINISTERING TO TREAT PARASITIC INFECTION OR DISEASE OR TO TREAT INFECTIONS AND DISEASES CAUSED BY CERTAIN BACTERIAL AND PLANT TOXINS; COMPOUNDS SUCH AS SALT OF 2-PHENYL-3,4-DIHYDROXY-5-HYDROXYMETHYL-PYRROLIDINE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2000-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | PYGB 1652/4885PYGL 1287/4885PYGM 1642/4885 |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | PYGB 1652/4885PYGL 1287/4885PYGM 1642/4885 |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | PYGB 1652/4885PYGL 1287/4885PYGM 1642/4885 |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | PYGB 1652/4885PYGL 1287/4885PYGM 1642/4885 |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | PYGB 1652/4885PYGL 1287/4885PYGM 1642/4885 |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | PYGB 1652/4885PYGL 1287/4885PYGM 1642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.