Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666022 | 0.90 | GPR35 (0.43) | ALDH1A1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL2417023 | 0.80 | ALDH1A1 (0.41) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL29566643 | 0.80 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL308233 | 0.80 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL9657643 | 0.78 | GLA (0.42) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL10480222 | 0.78 | GLA (0.40) | MAPTALDH1A1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL11507064 | 0.77 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5878676 | 0.77 | MEN1 (0.51) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL3667437 | 0.76 | GPR35 (0.45) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL3046272 | 0.75 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948236-A2 | METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN | Naturalite Benelux B.V. (NL) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007099398-A2 | METHODS AND COMPOSITIONS FOR TREATMENT OF SKIN | NATURALITE BENELUX B.V. (US) | 2007-09-07 | — | — | WO | disclosed |