Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608318 | 0.83 | MEN1 (0.34) | MEN1KMT2AESR1POLBGAA | |
| SCHEMBL27419051 | 0.79 | MEN1 (0.47) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL548545 | 0.77 | NPC1 (0.41) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL549467 | 0.77 | MEN1 (0.39) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL549740 | 0.76 | MEN1 (0.43) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL3762683 | 0.74 | MEN1 (0.46) | MEN1KMT2AESR1POLBGAA | |
| SCHEMBL3752409 | 0.73 | MEN1 (0.44) | MEN1KMT2AESR1POLBGAA | |
| SCHEMBL549698 | 0.73 | MEN1 (0.41) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL2048427 | 0.73 | ACHE (0.43) | MEN1KMT2AESR1POLBGAA | |
| SCHEMBL548584 | 0.73 | MEN1 (0.49) | MEN1KMT2APOLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1336597-B1 | Hydroxyphenyl adamantanes and process for the production of the same | HONSHU CHEMICAL IND (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-6720460-B2 | FORMING HEAT RESISTANT, MECHANICAL STRENGTH POLYMER ADDITIVES; ACID CATALYZED REACTION OF ADAMANTANE DIOL OR TRIOL WITH PHENOLIC DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1336597-A1 | Hydroxyphenyl adamantanes and process for the production of the same | Honshu Chemical Industry Co., Ltd. (JP) | 2003-08-20 | — | — | EP | disclosed |