Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607209 | 0.83 | MEN1 (0.36) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL549740 | 0.80 | MEN1 (0.43) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL4606716 | 0.80 | MEN1 (0.38) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL548759 | 0.77 | MEN1 (0.38) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL2048427 | 0.74 | ACHE (0.43) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL549698 | 0.74 | MEN1 (0.41) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL4606222 | 0.73 | KMT2A (0.34) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL548982 | 0.72 | MEN1 (0.43) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL4953935 | 0.71 | ESR1 (0.31) | MEN1KMT2AESR1 | |
| SCHEMBL548531 | 0.71 | MEN1 (0.39) | MEN1KMT2APOLBGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1336597-B1 | Hydroxyphenyl adamantanes and process for the production of the same | HONSHU CHEMICAL IND (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-6720460-B2 | FORMING HEAT RESISTANT, MECHANICAL STRENGTH POLYMER ADDITIVES; ACID CATALYZED REACTION OF ADAMANTANE DIOL OR TRIOL WITH PHENOLIC DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| US-20030187307-A1 | Hydroxyphenyl adamantanes and process for the production of the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1336597-A1 | Hydroxyphenyl adamantanes and process for the production of the same | Honshu Chemical Industry Co., Ltd. (JP) | 2003-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187307-A1 | Hydroxyphenyl adamantanes and process for the production of the same | CYP8B1, DHPS, P4HA1 | MEN1 1025/4885KMT2A 4019/4885POLB 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.