Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 10/20 | 1.00 |
| ▸ | GABRD | O14764 | 10/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 10/20 | 1.00 |
| ▸ | GABRB1 | P18505 | 10/20 | 1.00 |
| ▸ | GABRG2 | P18507 | 10/20 | 1.00 |
| ▸ | GABRB3 | P28472 | 10/20 | 1.00 |
| ▸ | GABRA5 | P31644 | 10/20 | 1.00 |
| ▸ | GABRA3 | P34903 | 10/20 | 1.00 |
| ▸ | GABRA2 | P47869 | 10/20 | 1.00 |
| ▸ | GABRB2 | P47870 | 10/20 | 1.00 |
| ▸ | GABRA4 | P48169 | 10/20 | 1.00 |
| ▸ | GABRE | P78334 | 10/20 | 1.00 |
| ▸ | GABRA6 | Q16445 | 10/20 | 1.00 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 1.00 |
| ▸ | GABRG3 | Q99928 | 10/20 | 1.00 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 1.00 |
| ▸ | TNKS | O95271 | 1/20 | 0.63 |
| ▸ | PARP1 | P09874 | 1/20 | 0.63 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656060 | 0.90 | GABRP (0.82) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30310999 | 0.90 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4627823 | 0.90 | GABRP (0.82) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16894631 | 0.90 | GABRP (0.81) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4454279 | 0.90 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5064064 | 0.89 | GABRP (0.80) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7538912 | 0.87 | GABRP (0.84) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7568626 | 0.77 | TNKS (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14433139 | 0.77 | GABRP (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4990126 | 0.77 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503771-B1 | SEDATIVE MATERIALS AND TREATMENTS | UNIV STRATHCLYDE (GB) | 2008-07-23 | — | — | EP | disclosed |
| EP-0857066-B1 | USE OF NITROFLAVONOIDS FOR THE TREATMENT OF ANXIETY | UNIV STRATHCLYDE (GB) | 2002-05-29 | — | — | EP | disclosed |
| US-6080780-A | ADMINISTERING TO THE PATIENT A NITROFLAVANOID TO TREAT THE ANXIETY | UNIVERSITY OF STRATHCLYDE (GB) | 2000-06-27 | — | — | US | disclosed |
| EP-0857066-A1 | USE OF NITROFLAVONOIDS FOR THE TREATMENT OF ANXIETY | University of Strathclyde (GB) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997014414-A1 | USE OF NITROFLAVONOIDS FOR THE TREATMENT OF ANXIETY | UNIVERSITY OF STRATHCLYDE (GB) | 1997-04-24 | — | — | WO | disclosed |