Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 14/20 | 0.70 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.60 |
| ▸ | KDM1A | O60341 | 6/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.51 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607075 | 1.00 | GRIA4 (0.70) | GRIA4GRIA2KDM1AMAOAMAOB | |
| SCHEMBL4607083 | 0.90 | GRIA4 (0.60) | GRIA4GRIA2 | |
| SCHEMBL4606652 | 0.90 | GRIA4 (0.60) | GRIA4GRIA2 | |
| SCHEMBL4606949 | 0.90 | GRIA4 (0.60) | GRIA4GRIA2KDM1AMAOARCOR1 | |
| SCHEMBL4606558 | 0.90 | GRIA4 (0.60) | GRIA4GRIA2KDM1AMAOARCOR1 | |
| SCHEMBL4606846 | 0.89 | GRIA4 (0.74) | GRIA4GRIA2 | |
| SCHEMBL4606850 | 0.89 | GRIA4 (0.74) | GRIA4GRIA2 | |
| SCHEMBL4605406 | 0.89 | GRIA4 (0.59) | GRIA4GRIA2KDM1AMAOAMAOB | |
| SCHEMBL4607162 | 0.89 | GRIA4 (0.59) | GRIA4GRIA2KDM1AMAOAMAOB | |
| SCHEMBL4607477 | 0.89 | GRIA4 (0.57) | GRIA4GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |