Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.54 |
| ▸ | BACE1 | P56817 | 7/20 | 0.54 |
| ▸ | BCHE | P06276 | 5/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606799 | 0.85 | ACHE (0.52) | ACHEBACE1BCHESIGMAR1KMT2A | |
| SCHEMBL4607660 | 0.85 | ACHE (0.52) | ACHEBACE1BCHESIGMAR1KMT2A | |
| SCHEMBL3964293 | 0.73 | ACHE (0.55) | ACHEBACE1BCHESIGMAR1KMT2A | |
| SCHEMBL11100154 | 0.73 | ACHE (1.00) | ACHEBACE1BCHESIGMAR1KMT2A | |
| SCHEMBL3959844 | 0.70 | ACHE (0.64) | ACHEBACE1BCHEKMT2AMEN1 | |
| SCHEMBL8569393 | 0.69 | ACHE (0.74) | ACHEBCHE | |
| SCHEMBL16017733 | 0.69 | DRD4 (0.57) | ACHESIGMAR1KMT2AMEN1POLB | |
| SCHEMBL4608634 | 0.68 | HPGD (0.47) | KMT2AMEN1POLBKDM4E | |
| SCHEMBL16017732 | 0.67 | KMT2A (0.52) | SIGMAR1KMT2AMEN1POLB | |
| SCHEMBL10107494 | 0.67 | SLC6A12 (0.66) | ACHESIGMAR1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | disclosed |
| EP-1440976-A1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-07-28 | — | — | EP | disclosed |
| EP-0927192-B1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-12 | — | — | EP | disclosed |