Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CCNC | P24863 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14873462 | 0.83 | HSD17B1 (0.55) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL12971 | 0.81 | ALDH1A1 (0.69) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3831380 | 0.80 | KDM4E (0.67) | KDM4ECCNCCDK8MEN1KMT2A | |
| SCHEMBL8047555 | 0.79 | KDM4E (0.65) | KDM4ECCNCCDK8MEN1KMT2A | |
| SCHEMBL3829254 | 0.79 | KDM4E (1.00) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2221168 | 0.79 | ALDH1A1 (0.47) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL29431736 | 0.79 | HSD17B1 (0.76) | MEN1KMT2AALDH1A1RAB9AHSD17B1 | |
| SCHEMBL16636791 | 0.79 | ALDH1A1 (0.56) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2288997 | 0.79 | ALDH1A1 (0.47) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL14970084 | 0.77 | NPC1 (0.50) | KDM4EMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022075-A1 | NOVEL PHENYLPYRROLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022075-A1 | NOVEL PHENYLPYRROLE DERIVATIVE | GCKR, GCK, SLC5A1 | KDM4E 2858/4885CCNC 3597/4885CDK8 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.