Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14862287 | 0.97 | CA12 (0.40) | CA12CA2CA9CA1TSHR | |
| Fluoride Ion SCHEMBL7030262 | 0.95 | CA12 (0.39) | CA12CA2CA9CA1TSHR | |
| Bromide SCHEMBL28959078 | 0.95 | CA12 (0.39) | CA12CA2CA9CA1TSHR | |
| Hydrochloric Acid SCHEMBL25405264 | 0.93 | CA12 (0.34) | CA12CA2CA9CA1TSHR | |
| Hydrochloric Acid SCHEMBL25405638 | 0.91 | CA12 (0.38) | CA12CA2CA9CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL25403550 | 0.89 | CA12 (0.39) | CA12CA2CA9CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29466158 | 0.84 | CA12 (0.34) | CA12CA2CA9CA1TSHR | |
| Hydrochloric Acid SCHEMBL25406366 | 0.82 | CA12 (0.38) | CA12CA2CA9CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1535756 | 0.76 | CA12 (0.40) | CA12CA2CA9CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL25405995 | 0.76 | CA12 (0.36) | CA12CA2CA9CA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | EVONIK OPERATIONS GMBH (DE) | 2023-08-24 | — | — | US | claimed |
| CN-114195819-A | Method for preparing polysulfanylsilanes by phase transfer catalysis | 赢创运营有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-114163296-A | Preparation method of 1, 3-dichloro-2, 4, 6-trifluorobenzene | 阜新睿光氟化学有限公司 | 2022-03-11 | — | — | CN | claimed |
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | EVONIK OPERATIONS GMBH (DE) | 2023-08-24 | — | — | US | disclosed |
| CN-111057219-B | Thermosetting oligomer, thermosetting composition, thermosetting material and article comprising the same, and method for producing the same | 高新特殊工程塑料全球技术有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114195819-A | Method for preparing polysulfanylsilanes by phase transfer catalysis | 赢创运营有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114163296-A | Preparation method of 1, 3-dichloro-2, 4, 6-trifluorobenzene | 阜新睿光氟化学有限公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-1945693-B1 | POLYARYLATE-SILOXANE COPOLYMERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-08-13 | — | — | EP | disclosed |
| EP-1957558-A2 | POLYARYLATE ACID CHLORIDE COMPOSITIONS AND DERIVATES THEREFROM | General Electric Company (US) | 2008-08-20 | — | — | EP | disclosed |
| EP-1945693-A1 | POLYARYLATE-SILOXANE COPOLYMERS | Momentive Performance Materials Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| US-7273919-B1 | High heat polyethersulfone compositions | GENERAL ELECTRIC COMPANY (US) | 2007-09-25 | — | — | US | disclosed |
| US-20070219344-A1 | HIGH HEAT POLYETHERSULFONE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2007-09-20 | — | — | US | disclosed |
| WO-2007070377-A2 | POLYARYLATE ACID CHLORIDE COMPOSITIONS AND DERIVATES THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070135610-A1 | Polyarylate acid chloride compositions and derivatives therefrom | GENERAL ELECTRIC COMPANY (US) | 2007-06-14 | — | — | US | disclosed |
| WO-2007047083-A1 | POLYARYLATE-SILOXANE COPOLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20070083026-A1 | Polyarylate-siloxane copolymers | GENERAL ELECTRIC COMPANY (US) | 2007-04-12 | — | — | US | disclosed |
| US-6265627-B1 | HEATING HALOGEN-CONTAINING AROMATIC COMPOUNDS WITH AN ALKALI METAL FLUORIDE IN PRESENCE OF N,N'N?-HEXA-SUBSTITUTED GUANIDINIUM HALIDE AS CATALYST TO PRODUCE POLYFLUOROAROMATIC COMPOUND | Igumnov, Sergei Mikhailovich (RU) | 2001-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265113-A1 | PROCESS FOR PREPARING POLYSULFANE SILANES BY MEANS OF PHASE TRANSFER CATALYSIS | MRPS22, MRPS23, SRM | CA12 1733/4885CA2 2132/4885CA9 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.