Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743136 | 0.83 | TDP1 (0.47) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL4605823 | 0.81 | TDP1 (0.49) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL4606686 | 0.81 | TDP1 (0.49) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL7152328 | 0.80 | TDP1 (0.71) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL7152392 | 0.80 | TDP1 (0.71) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL7146573 | 0.80 | TDP1 (0.71) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL7151458 | 0.80 | TDP1 (0.71) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL7155403 | 0.79 | TDP1 (0.74) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL7155400 | 0.79 | TDP1 (0.74) | TDP1POLBMAPK1ABCB1PGD | |
| SCHEMBL18982003 | 0.76 | TDP1 (0.76) | TDP1POLBMAPK1ABCB1PGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1947082-A2 | Oximes or imines of 4-pentulosonic acid methyl esters as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947084-A2 | 2-Pyrrolidones as intermediates for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6583297-B2 | From tri-O-acetyl-D-erythro-4-pentulosonic acid esters | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2003-06-24 | — | — | US | disclosed |
| US-6518437-B1 | 2,3,5-Tri-O-acetyl-1,4-Dideoxy-1,4-imino-D-ribitol. for chemical intermediates | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-02-11 | — | — | US | disclosed |
| US-6492534-B2 | CHEMICAL INTERMEDIATE FOR BIOSYNTHESIS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6482974-B2 | FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-11-19 | — | — | US | disclosed |
| US-6423867-B1 | FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-07-23 | — | — | US | disclosed |
| US-6414163-B1 | PREPARING 1,4-DIDEOXY-1,4-IMINOPENTITOL BY REDUCTIVE CYCLIZATION OF SPECIFIED OXIME OR IMINE WITH REDUCING AGENT WHICH IS SOURCE OF SINGLET HYDROGEN OR HYDRIDE VIA INTERMEDIATE PYRROLIDONE LACTAM | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-07-02 | — | — | US | disclosed |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2002-02-28 | — | — | US | disclosed |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERS | 2002-02-28 | — | — | US | disclosed |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING | 2002-02-14 | — | — | US | disclosed |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885POLB 92/4885MAPK1 2028/4885 |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885POLB 92/4885MAPK1 2028/4885 |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885POLB 92/4885MAPK1 2028/4885 |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885POLB 92/4885MAPK1 2028/4885 |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885POLB 92/4885MAPK1 2028/4885 |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | TDP1 818/4885POLB 92/4885MAPK1 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.