SCHEMBL4608338

SCHEMBL4608338

COCc1ncccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 4/20 0.50
NPSR1 Q6W5P4 2/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
BLM P54132 1/20 0.50
AGER Q15109 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
NAPRT Q6XQN6 2/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
MYC P01106 1/20 0.45
KDM5A P29375 1/20 0.44
KDM5B Q9UGL1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30638431 1.00 KDM4E (0.52) KDM4ETDP1ALDH1A1NPSR1CYP3A4
SCHEMBL30840015 0.85 SYK (0.53) KDM4EALDH1A1
SCHEMBL22912507 0.85 TDP1 (0.51) KDM4ETDP1ALDH1A1MAPTALOX15
SCHEMBL2749775 0.85 KDM4E (0.50) KDM4ETDP1ALDH1A1NPSR1CYP3A4
Hydrochloric Acid SCHEMBL31245526 0.83 KDM4E (0.49) KDM4ETDP1ALDH1A1NPSR1CYP3A4
Hydrochloric Acid SCHEMBL21958035 0.83 KDM4E (0.49) KDM4ETDP1ALDH1A1NPSR1CYP3A4
SCHEMBL9694340 0.83 KDM4E (0.49) KDM4ETDP1ALDH1A1NPSR1CYP3A4
SCHEMBL3886138 0.83 KDM4E (0.49) KDM4ETDP1ALDH1A1NPSR1CYP3A4
SCHEMBL10699919 0.83 RAB9A (0.57) KDM4ETDP1ALDH1A1NPSR1MAPT
SCHEMBL15746654 0.82 P2RX7 (0.44) TDP1MAPTL3MBTL1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948801-A2 HERBICIDE-RESISTANT SUNFLOWER PLANTS WITH A NOVEL MUTATION IN THE GENE ENCODING THE LARGE SUBUNIT OF ACETOHYDROXYACID SYNTHASE, ISOLATED POLYNUCLEOTIDES, AND METHODS OF USE BASF Agrochemical Products, B.V. (NL) 2008-07-30 EP claimed
WO-2007054555-A9 HERBICIDE-RESISTANT SUNFLOWER PLANTS WITH A NOVEL MUTATION IN THE GENE ENCODING THE LARGE SUBUNIT OF ACETOHYDROXYACID SYNTHASE, ISOLATED POLYNUCLEOTIDES, AND METHODS OF USE BASF AGROCHEMICAL PRODUCTS BV (NL) 2007-07-05 WO claimed
WO-2007054555-A2 HERBICIDE-RESISTANT SUNFLOWER PLANTS WITH A NOVEL MUTATION IN THE GENE ENCODING THE LARGE SUBUNIT OF ACETOHYDROXYACID SYNTHASE, ISOLATED POLYNUCLEOTIDES, AND METHODS OF USE BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2007-05-18 WO claimed
EP-1766030-A2 POLYNUCLEOTIDES ENCODING MATURE AHASL PROTEINS FOR CREATING IMIDAZOLINONE-TOLERANT PLANTS BASF Plant Science GmbH (DE) 2007-03-28 EP claimed
WO-2006007373-A2 POLYNUCLEOTIDES ENCODING MATURE AHASL PROTEINS FOR CREATING IMIDAZOLINONE-TOLERANT PLANTS BASF PLANT SCIENCE GMBH (DE) 2006-01-19 WO claimed
CN-117820199-A Amide compound and application thereof in preparation of Sigma2 and 5HT2A inhibitors 瀚远医药有限公司 2024-04-05 CN disclosed
CN-117157287-A Pesticidally active cyclic amine compounds 先正达农作物保护股份公司 2023-12-01 CN disclosed
CN-1832945-A Diphenylpyridine derivatives, their preparation and their therapeutic use SANOFI AVENTIS (FR) 2006-09-13 CN disclosed
EP-1420629-A4 WHEAT PLANTS HAVING INCREASED RESISTANCE TO IMIDAZOLINONE HERBICIDES NORTHWEST PLANT BREEDING CO (US) 2004-12-29 EP disclosed
EP-1420629-A2 WHEAT PLANTS HAVING INCREASED RESISTANCE TO IMIDAZOLINONE HERBICIDES Northwest Plant Breeding Co. (US) 2004-05-26 EP disclosed
WO-2003013225-A2 WHEAT PLANTS HAVING INCREASED RESISTANCE TO IMIDAZOLINONE HERBICIDES NORTHWEST PLANT BREEDING COMPANY (US) 2003-02-20 WO disclosed
US-6455469-B1 SUBSTITUTED ACETANILIDE DERIVATIVE IN COMBINATION WITH OTHER HERBICIDE TO GIVE EFFECTIVE WEED CONTORL ISHIHARA SANGYO KAISHA, LTD. (JP) 2002-09-24 US disclosed