SCHEMBL4608342

SCHEMBL4608342

O=[PH](OC1CCCCC1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
RECQL P46063 1/20 0.38
FABP7 O15540 1/20 0.37
FABP5 Q01469 1/20 0.37
IDO1 P14902 2/20 0.37
FAAH O00519 1/20 0.35
MGLL Q99685 1/20 0.35
ALDH1A1 P00352 1/20 0.34
RAB9A P51151 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.33
METAP2 P50579 2/20 0.33
METAP1 P53582 1/20 0.33
PKM P14618 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779701 0.75 NPC1 (0.36) NPSR1CYP3A4CYP2C9CYP2C19RECQL
SCHEMBL19878091 0.74 RAB9A (0.39) NPSR1CYP3A4CYP2C9CYP2C19RECQL
SCHEMBL779211 0.74 PTGDR2 (0.40) NPSR1CYP3A4CYP2C9CYP2C19RECQL
SCHEMBL778324 0.73 KMT2A (0.38) CYP3A4
SCHEMBL26498162 0.70 ALDH1A1 (0.38) CYP3A4CYP2C9CYP2C19ALDH1A1KDM4E
SCHEMBL779275 0.70 HSP90AA1 (0.41) IDO1RAB9AKDM4E
SCHEMBL779276 0.70 POLB (0.37) NPSR1CYP3A4CYP2C9CYP2C19RECQL
SCHEMBL8637926 0.69 IDO1 (0.36) NPSR1IDO1ALDH1A1RAB9AKDM4E
SCHEMBL778810 0.67 EPHX2 (0.42) RAB9A
Biphenyl SCHEMBL11505660 0.67 HDAC4 (0.38) NPSR1ALDH1A1RAB9AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181250-A Alkenyl phosphine compound and preparation method thereof 中国石油化工股份有限公司 2022-03-15 CN claimed
CN-114181250-A Alkenyl phosphine compound and preparation method thereof 中国石油化工股份有限公司 2022-03-15 CN disclosed
US-10479809-B2 Method for producing alkenyl phosphorus compound MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-11-19 US disclosed
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-08-29 US disclosed
EP-3348561-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND Maruzen Petrochemical Co., Ltd. (JP) 2018-07-18 EP disclosed
US-7687229-B2 Silver halide color photographic light-sensitive material and image forming method FUJIFILM CORPORATION (JP) 2010-03-30 US disclosed
US-7556918-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability FUJIFILM CORPORATION (JP) 2009-07-07 US disclosed
US-7425408-B2 Silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2008-09-16 US disclosed
EP-1369422-B1 PROCESS FOR PREPARATION OF ALKENYLPHOSPHINE OXIDES OR ALKENYLPHOSPHINIC ACID ESTERS JAPAN SCIENCE & TECH AGENCY (JP) 2008-07-23 EP disclosed
US-20080113305-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJIFILM CORPORATION 2008-05-15 US disclosed
US-20070298348-A1 Silver Halide Color Photographic Light-Sensitive Material and Image Forming Method FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-20070054224-A1 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2007-03-08 US disclosed
US-7135583-B2 Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2006-11-14 US disclosed
US-20040059146-A1 Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-03-25 US disclosed
EP-1369422-A1 PROCESS FOR PREPARATION OF ALKENYLPHOSPHINE OXIDES OR ALKENYLPHOSPHINIC ACID ESTERS Japan Science and Technology Corporation (JP) 2003-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479809-B2 Method for producing alkenyl phosphorus compound ORC3, OR10J3, ORAI3 NPSR1 3544/4885CYP3A4 53/4885CYP2C9 570/4885
US-20040059146-A1 Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters PHOSPHO1, AGPS, AGPAT5 NPSR1 2698/4885CYP3A4 1357/4885CYP2C9 1072/4885
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND ORC3, OR10J3, ALK NPSR1 3760/4885CYP3A4 71/4885CYP2C9 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.