Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 3/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689185 | 0.79 | AKR1C3 (0.36) | LMNAALDH1A1PTPRCS100A4BCHE | |
| SCHEMBL4608374 | 0.78 | VCAM1 (0.37) | LMNAGAAVCAM1ALDH1A1RECQL | |
| SCHEMBL7741732 | 0.71 | PTPRC (0.63) | LMNAALDH1A1PTPRCS100A4SMN1; SMN2 | |
| SCHEMBL1293605 | 0.70 | VCAM1 (0.64) | LMNAGAAVCAM1ALDH1A1RECQL | |
| SCHEMBL3689183 | 0.68 | PTPRC (0.36) | LMNAALDH1A1PTPRCS100A4BCHE | |
| SCHEMBL1981640 | 0.68 | VCAM1 (0.56) | LMNAGAAVCAM1ALDH1A1RECQL | |
| SCHEMBL31184430 | 0.68 | VCAM1 (0.60) | LMNAGAAVCAM1ALDH1A1RECQL | |
| SCHEMBL1179904 | 0.68 | VCAM1 (0.59) | LMNAGAAVCAM1ALDH1A1RECQL | |
| SCHEMBL15063984 | 0.66 | MEN1 (0.34) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL459005 | 0.66 | MAPT (0.43) | ALDH1A1RECQLBCHEACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |