Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PTPRC | P08575 | 3/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608378 | 0.79 | LMNA (0.41) | ALDH1A1PTPRCS100A4MEN1KMT2A | |
| SCHEMBL3689183 | 0.78 | PTPRC (0.36) | AKR1C3AKR1C2ALDH1A1PTPRCS100A4 | |
| SCHEMBL7741732 | 0.71 | PTPRC (0.63) | ALDH1A1PTPRCS100A4PDE7AMEN1 | |
| SCHEMBL85657 | 0.70 | PDE7A (0.50) | ALDH1A1PTPRCS100A4POLBPDE7A | |
| SCHEMBL4608374 | 0.68 | VCAM1 (0.37) | ALDH1A1PTPRCS100A4MAPTLMNA | |
| SCHEMBL14021283 | 0.68 | ALDH1A1 (0.50) | AKR1C3AKR1C2ALDH1A1POLBPDE7A | |
| SCHEMBL15123102 | 0.68 | PDE7A (0.47) | ALDH1A1PTPRCS100A4POLBPDE7A | |
| SCHEMBL30619342 | 0.68 | PDE7A (0.47) | ALDH1A1PTPRCS100A4POLBPDE7A | |
| SCHEMBL458040 | 0.66 | AR (0.33) | ARFFAR4 | |
| SCHEMBL459005 | 0.66 | MAPT (0.43) | ALDH1A1POLBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2187748-A2 | FUNGICIDAL COMPOUNDS AND MIXTURES | E. I. du Pont de Nemours and Company (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | disclosed |