Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | PARP1 | P09874 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TNKS | O95271 | 2/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GPR3 | P46089 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 3/20 | 0.56 |
| ▸ | CCND1 | P24385 | 3/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.56 |
| ▸ | PRKCG | P05129 | 1/20 | 0.56 |
| ▸ | PRKCB | P05771 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325768 | 0.85 | PARP1 (0.47) | KDM4EPARP1ALDH1A1TNKSTNKS2 | |
| SCHEMBL23132411 | 0.81 | PARP1 (0.57) | KDM4EPARP1ALDH1A1TNKSTNKS2 | |
| SCHEMBL500585 | 0.78 | PARP1 (0.49) | KDM4EPARP1ALDH1A1TNKSTNKS2 | |
| SCHEMBL17072688 | 0.78 | CDK4 (0.65) | ALDH1A1MEN1GPR3KMT2AHSD17B10 | |
| SCHEMBL20227597 | 0.77 | KDM4E (0.44) | KDM4EPARP1ALDH1A1TNKSTNKS2 | |
| SCHEMBL10945861 | 0.76 | CDK4 (0.63) | MEN1KMT2ACDK4CCND1CCNB2 | |
| SCHEMBL17071327 | 0.76 | KIF11 (0.65) | MEN1KMT2ACDK4CCND1CCNB2 | |
| SCHEMBL29385261 | 0.76 | CDK4 (0.68) | KDM4EPARP1ALDH1A1LMNAMEN1 | |
| SCHEMBL257083 | 0.76 | CDK4 (0.68) | KDM4EPARP1ALDH1A1LMNAMEN1 | |
| SCHEMBL23132387 | 0.76 | CDK4 (0.58) | KDM4EPARP1ALDH1A1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| EP-2387564-A1 | BENZO ÝC¨PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | Rutgers, The State University of New Jersey (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8037884-B2 | Modular system for patient positioning during medical procedures | ALLEN MEDICAL SYSTEMS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | KDM4E 536/4885PARP1 1409/4885ALDH1A1 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.