Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | TNKS | O95271 | 2/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500222 | 0.79 | KDR (0.55) | PARP1KDM4EALDH1A1CYP1A2TNKS | |
| SCHEMBL460847 | 0.78 | KDM4E (0.57) | PARP1KDM4EALDH1A1CYP1A2TNKS | |
| SCHEMBL27694292 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL27717804 | 0.78 | KIF11 (0.57) | CYP1A2CDK4CCND1ERBB2FYN | |
| SCHEMBL20227597 | 0.76 | KDM4E (0.44) | PARP1KDM4EALDH1A1CYP1A2TNKS | |
| SCHEMBL2956150 | 0.76 | ALDH1A1 (0.64) | KDM4EALDH1A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL441488 | 0.74 | HSD17B10 (0.56) | ALDH1A1CYP1A2HSD17B10ERBB2FYN | |
| SCHEMBL5334139 | 0.74 | ALDH1A1 (0.56) | KDM4EALDH1A1CYP1A2HSD17B10MAPT | |
| SCHEMBL9777839 | 0.72 | ALDH1A1 (0.54) | PARP1KDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL444017 | 0.72 | ALDH1A1 (0.60) | ALDH1A1CYP1A2HSD17B10MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106199-B2 | Infrared phosphorescent organic light emitting device; Platinum, Paladium, Iridium, Rhodium complex; cyclometalating ligands pyrenyl-pyridine, 1-pyrenyl-quinolone, pyrenyl-benziso-quinolone, 1-pyrenyl-iso-quinolone; acetylacetonate ancillary ligand; tunable emission intensity; undetectable to unaided eye | ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2012-01-31 | — | — | US | claimed |
| US-20080269491-A1 | Organometallic Materials for Optical Emission, Optical Absorption, and Devices Including Organometallic Materials | ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-10-30 | — | — | US | claimed |
| US-8106199-B2 | Infrared phosphorescent organic light emitting device; Platinum, Paladium, Iridium, Rhodium complex; cyclometalating ligands pyrenyl-pyridine, 1-pyrenyl-quinolone, pyrenyl-benziso-quinolone, 1-pyrenyl-iso-quinolone; acetylacetonate ancillary ligand; tunable emission intensity; undetectable to unaided eye | ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2012-01-31 | — | — | US | disclosed |
| US-20080269491-A1 | Organometallic Materials for Optical Emission, Optical Absorption, and Devices Including Organometallic Materials | ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269491-A1 | Organometallic Materials for Optical Emission, Optical Absorption, and Devices Including Organometallic Materials | TPR, PICALM, AP3M1 | PARP1 1385/4885KDM4E 2859/4885ALDH1A1 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.