SCHEMBL4608511

SCHEMBL4608511

CC(=O)C[C@@H](C)CCC=C(C)C

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.57
ALDH1A1 P00352 3/20 0.57
GGPS1 O95749 2/20 0.49
FDPS P14324 2/20 0.49
TSHR P16473 1/20 0.47
USP2 O75604 1/20 0.46
GLA P06280 2/20 0.44
TDP1 Q9NUW8 2/20 0.42
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5136231 1.00 ALOX15 (0.57) ALOX15ALDH1A1GGPS1FDPSTSHR
Formaldehyde SCHEMBL5704728 0.96 ALOX15 (0.53) ALOX15ALDH1A1GGPS1FDPSTSHR
SCHEMBL991834 0.87 ALOX15 (0.57) ALOX15ALDH1A1GGPS1FDPSTSHR
SCHEMBL6050718 0.87 ALOX15 (0.57) ALOX15ALDH1A1GGPS1FDPSTSHR
Citronellic Acid SCHEMBL193354 0.85 ALOX15 (0.55) ALOX15ALDH1A1GGPS1FDPSTSHR
Citronellic Acid SCHEMBL712982 0.85 ALOX15 (0.55) ALOX15ALDH1A1GGPS1FDPSTSHR
Citronellic Acid SCHEMBL714852 0.85 ALOX15 (0.55) ALOX15ALDH1A1GGPS1FDPSTSHR
SCHEMBL5704674 0.83 ALOX15 (0.46) ALOX15ALDH1A1GGPS1FDPSTSHR
SCHEMBL1477739 0.83 ALOX15 (0.53) ALOX15ALDH1A1GGPS1FDPSTSHR
SCHEMBL14418807 0.83 ALOX15 (0.53) ALOX15ALDH1A1GGPS1FDPSTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017205964-A1 AMINOSTEROID DERIVATIVES AND PROCESS FOR PRODUCING SAME UNIVERSITé LAVAL (CA) 2017-12-07 WO disclosed
US-8653054-B2 2-(N-substituted piperazinyl) steroid derivatives UNIVERSITE LAVAL (CA) 2014-02-18 US disclosed
US-8653054-B2 2-(N-substituted piperazinyl) steroid derivatives UNIVERSITE LAVAL (CA) 2014-02-18 US disclosed
US-20110312926-A1 2-(N-Substituted Piperazinyl) Steroid Derivatives UNIVERSITE LAVAL (CA) 2011-12-22 US disclosed
US-20110312926-A1 2-(N-Substituted Piperazinyl) Steroid Derivatives UNIVERSITE LAVAL (CA) 2011-12-22 US disclosed
EP-1347035-B1 Isomer composition containing optically active ethyl trans-2,2,6-trimethylcyclohexylcarboxylate and fragrance composition containing the isomer composition TAKASAGO PERFUMERY CO LTD (JP) 2008-07-23 EP disclosed
EP-1347036-B1 Isomer composition excellent in chemical resistance containing optically active trans-1(2,2,6-trimethylcyclohexyl)-2-buten-1-one and fragrance composition containing the isomer composition TAKASAGO PERFUMERY CO LTD (JP) 2008-06-25 EP disclosed
US-6930083-B2 Isomer composition excellent in chemical resistance containing optically active trans-1-(2,2,6-trimethylcyclohexyl)-2-buten-1-one and fragrance compositions containing the isomer composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-08-16 US disclosed
EP-1162191-B1 (1S,6R)- And/or (1R,6S)-2,2,6-trimethylcyclohexyl methyl ketone, process for producing the same, and perfume composition containing the same TAKASAGO PERFUMERY CO LTD (JP) 2005-06-29 EP disclosed
EP-1468978-A1 Process for producing (1S,6R)-2,2,6-trimethylcyclohexyl methyl ketone and/or (1R,6S)-2,2,6-trimethylcyclohexyl methyl ketone Takasago International Corporation (JP) 2004-10-20 EP disclosed
US-6770618-B2 ORGANOLEPTIC; PLANT EXTRACTS; MIXTURES TAKASAGO INTERNATIONAL CORP. (JP) 2004-08-03 US disclosed
US-20030207790-A1 Isomer composition excellent in chemical resistance containing optically active trans-1-(2,2,6-trimethylcyclohexyl)-2-buten-1-one and fragrance compositions containing the isomer composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-11-06 US disclosed
US-20030207789-A1 Isomer composition containing optically active ethyl trans-2,2,6-trimethylcyclohexylcarboxylate and fragrance composition containing the isomer composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-11-06 US disclosed
EP-1347036-A2 Isomer composition excellent in chemical resistance containing optically active trans-1(2,2,6-trimethylcyclohexyl)-2-buten-1-one and fragrance composition containing the isomer composition Takasago International Corporation (JP) 2003-09-24 EP disclosed
EP-1347035-A2 Isomer composition containing optically active ethyl trans-2,2,6-trimethylcyclohexylcarboxylate and fragrance composition containing the isomer composition Takasago International Corporation (JP) 2003-09-24 EP disclosed
US-20020042356-A1 (1S,6R)-2,2,6-Trimethylcyclohexyl methyl ketone and/or (1R,6S)-2,2,6-trimethylcyclohexyl methyl ketone, process for producing the same, and perfume composition containing the same TAKASAGO INTERNATIONAL CORP. (JP) 2002-04-11 US disclosed
EP-1162191-A2 (1S,6R)- And/or (1R,6S)-2,2,6-trimethylcyclohexyl methyl ketone, process for producing the same, and perfume composition containing the same Takasago International Corporation (JP) 2001-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042356-A1 (1S,6R)-2,2,6-Trimethylcyclohexyl methyl ketone and/or (1R,6S)-2,2,6-trimethylcyclohexyl methyl ketone, process for producing the same, and perfume composition containing the same MINK1, TEKT1, TMT1A ALOX15 1692/4885ALDH1A1 1508/4885GGPS1 246/4885
US-20030207790-A1 Isomer composition excellent in chemical resistance containing optically active trans-1-(2,2,6-trimethylcyclohexyl)-2-buten-1-one and fragrance compositions containing the isomer composition TAS1R1, TAS1R2, TAS2R1 ALOX15 689/4885ALDH1A1 128/4885GGPS1 890/4885
US-20030207789-A1 Isomer composition containing optically active ethyl trans-2,2,6-trimethylcyclohexylcarboxylate and fragrance composition containing the isomer composition ETV1, ELP1, TAS1R2 ALOX15 1129/4885ALDH1A1 599/4885GGPS1 1137/4885
US-20110312926-A1 2-(N-Substituted Piperazinyl) Steroid Derivatives NR5A1, HSD17B11, CYP17A1 ALOX15 2932/4885ALDH1A1 556/4885GGPS1 713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.