Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864081 | 1.00 | HSD11B1 (0.33) | HSD11B1HSP90AA1NR3C1 | |
| SCHEMBL4855306 | 0.87 | NR3C1 (0.35) | HSD11B1HSP90AA1NR3C1 | |
| SCHEMBL4564249 | 0.86 | NR3C1 (0.31) | NR3C1 | |
| SCHEMBL4866562 | 0.86 | HSP90AA1 (0.34) | HSP90AA1NR3C1 | |
| SCHEMBL4900036 | 0.85 | NR3C1 (0.35) | NR3C1 | |
| SCHEMBL4556232 | 0.84 | CYP19A1 (0.34) | — | |
| SCHEMBL4865539 | 0.84 | CYP19A1 (0.34) | — | |
| SCHEMBL4564288 | 0.84 | HDAC4 (0.33) | NR3C1 | |
| SCHEMBL4864334 | 0.84 | ADRA1D (0.35) | NR3C1 | |
| SCHEMBL4858243 | 0.84 | HDAC4 (0.33) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907395-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007002867-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |