Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778747 | 0.82 | MAOB (0.50) | TAAR1LTA4HPLA2G2AALDH1A1HTR1A | |
| SCHEMBL4723525 | 0.82 | ALDH1A1 (0.50) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL4723329 | 0.82 | NPC1 (0.49) | LTA4HALDH1A1LMNAKCNH2HRH3 | |
| SCHEMBL4609655 | 0.82 | KCNH2 (0.38) | ALDH1A1LMNASMN1; SMN2KCNH2HRH3 | |
| SCHEMBL9778777 | 0.81 | DRD2 (0.43) | MEN1ALDH1A1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9778655 | 0.81 | KDM4E (0.44) | KCNH2 | |
| SCHEMBL9778597 | 0.81 | MAOB (0.51) | LTA4HALDH1A1L3MBTL1KCNH2HRH3 | |
| SCHEMBL4741399 | 0.81 | KCNH2 (0.40) | ALDH1A1LMNAKCNH2HRH3HTR1A | |
| SCHEMBL10757930 | 0.78 | NR5A1 (0.53) | LTA4HALDH1A1LMNAKCNH2HRH3 | |
| SCHEMBL4719781 | 0.78 | NQO1 (0.54) | LTA4HALDH1A1LMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140147452-A1 | METHOD FOR REMOVAL OF TOXINS FROM MUCOSAL MEMBRANES | POLYRIZON LTD. (IL) | 2014-05-29 | — | — | US | disclosed |
| US-8679484-B2 | Method for removal of toxins from mucosal membranes | POLYRIZON LTD. (IL) | 2014-03-25 | — | — | US | disclosed |
| US-20080317765-A1 | Method for Removal of Toxins from Mucosal Membranes | POLYRIZON LTD. (IL) | 2008-12-25 | — | — | US | disclosed |
| EP-1877446-A1 | METHOD FOR REMOVAL OF TOXINS FROM MUCOSAL MEMBRANES | POLYRIZON LTD. (IL) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006092799-A1 | METHOD FOR REMOVAL OF TOXINS FROM MUCOSAL MEMBRANES | POLYRIZON LTD. (IL) | 2006-09-08 | — | — | WO | disclosed |