Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741399 | 0.91 | KCNH2 (0.40) | KCNH2HRH3HTR1AMAOBMAPT | |
| SCHEMBL9778747 | 0.82 | MAOB (0.50) | HTR1AMAOBPKMALDH1A1MAOA | |
| SCHEMBL4608650 | 0.82 | TAAR1 (0.47) | KCNH2HRH3HTR1ALMNAALDH1A1 | |
| SCHEMBL4723525 | 0.82 | ALDH1A1 (0.50) | KCNH2HRH3MAOBMAPTLMNA | |
| SCHEMBL4723329 | 0.82 | NPC1 (0.49) | KCNH2HRH3MAOBMAPTLMNA | |
| SCHEMBL9778777 | 0.81 | DRD2 (0.43) | KCNH2HRH3ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9778655 | 0.81 | KDM4E (0.44) | KCNH2MAOBMAPTPKMAPP | |
| SCHEMBL9778597 | 0.81 | MAOB (0.51) | KCNH2HRH3HTR1AMAOBALDH1A1 | |
| SCHEMBL7397796 | 0.80 | ALDH1A1 (0.40) | HTR1AMAOBMAPTCRBNALDH1A1 | |
| SCHEMBL3859829 | 0.79 | KCNH2 (0.38) | KCNH2HRH3MAPTLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140147452-A1 | METHOD FOR REMOVAL OF TOXINS FROM MUCOSAL MEMBRANES | POLYRIZON LTD. (IL) | 2014-05-29 | — | — | US | disclosed |
| US-8679484-B2 | Method for removal of toxins from mucosal membranes | POLYRIZON LTD. (IL) | 2014-03-25 | — | — | US | disclosed |
| US-20080317765-A1 | Method for Removal of Toxins from Mucosal Membranes | POLYRIZON LTD. (IL) | 2008-12-25 | — | — | US | disclosed |
| EP-1877446-A1 | METHOD FOR REMOVAL OF TOXINS FROM MUCOSAL MEMBRANES | POLYRIZON LTD. (IL) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006092799-A1 | METHOD FOR REMOVAL OF TOXINS FROM MUCOSAL MEMBRANES | POLYRIZON LTD. (IL) | 2006-09-08 | — | — | WO | disclosed |