SCHEMBL460873

SCHEMBL460873

CC(C)(C)c1ccc(-c2nnc(-c3cc(-c4nnc(-c5ccc(C(C)(C)C)cc5)o4)cc(-c4nnc(-c5ccc(C(C)(C)C)cc5)o4)c3)o2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.68
RAB9A P51151 8/20 0.68
KDM4E B2RXH2 3/20 0.68
S1PR1 P21453 2/20 0.61
NR1H4 Q96RI1 1/20 0.53
EGFR P00533 1/20 0.51
NOTUM Q6P988 1/20 0.50
MAPT P10636 2/20 0.49
ALDH1A1 P00352 1/20 0.49
S1PR4 O95977 1/20 0.48
S1PR5 Q9H228 1/20 0.48
TP53 P04637 3/20 0.48
POLB P06746 2/20 0.48
GFER P55789 1/20 0.47
IKBKB O14920 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HPGD P15428 3/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12427246 1.00 NPC1 (0.68) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL12570671 0.96 NPC1 (0.64) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL31606600 0.96 NPC1 (0.64) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL3293191 0.94 NPC1 (0.75) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL2623780 0.94 NPC1 (0.75) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL12309408 0.93 NPC1 (0.60) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL1104799 0.92 NPC1 (0.72) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL6296907 0.92 NPC1 (0.72) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL966175 0.91 KDM4E (0.58) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL30083 0.91 NPC1 (0.62) NPC1RAB9AKDM4ES1PR1NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960080-B2 Oxadiazole containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
US-20090246664-A1 OXADIAZOLE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US claimed
US-7521113-B2 Light-emitting devices with fullerene layer LU, ZHENG-HONG (CA) 2009-04-21 US claimed
US-20060099448-A1 Top light-emitting devices with fullerene layer LU ZHENG-HONG 2006-05-11 US claimed
US-20040214041-A1 Light-emitting devices with fullerene layer THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2004-10-28 US claimed
CN-118215332-A Display apparatus 乐金显示有限公司 2024-06-18 CN disclosed
US-11866598-B2 Compositions and methods including depositing nanomaterial SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-09 US disclosed
US-20230134846-A1 LIGHT EMITTING ELEMENT AND DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2023-05-04 US disclosed
US-20230134846-A1 LIGHT EMITTING ELEMENT AND DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2023-05-04 US disclosed
US-20220376180-A1 DEVICE CONTAINING METAL OXIDE-CONTAINING LAYERS EVONIK OPERATIONS GMBH (DE) 2022-11-24 US disclosed
US-11472979-B2 Compositions and methods including depositing nanomaterial SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-10-18 US disclosed
US-20220127483-A1 COMPOSITIONS AND METHODS INCLUDING DEPOSITING NANOMATERIAL SAMSUNG ELECTRONICS CO LTD (KR) 2022-04-28 US disclosed
US-20020091256-A1 Azepine compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-07-11 US disclosed
US-6399226-B1 Material for organic electroluminescence device and method for producing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-04 US disclosed
US-20010033347-A1 Display element and layered type display element MINOLTA CO., LTD. 2001-10-25 US disclosed
US-20010003601-A1 ORGANIC ELECTROLUMINECENT ELEMENT AND METHOD OF MANUFACTURING SAME MINOLTA CO., LTD. (JP) 2001-06-14 US disclosed
US-6180217-B1 Organic electroluminescent element MINOLTA CO., LTD. (JP) 2001-01-30 US disclosed
EP-1043915-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND METHOD FOR PRODUCING THE SAME Daicel Chemical Industries, Ltd. (JP) 2000-10-11 EP disclosed
US-6060826-A Organic electroluminescent element having an excimer light irradiated positive electrode and method of manufacturing the same MINOLTA CO., LTD. (JP) 2000-05-09 US disclosed
WO-1998021587-A1 NANOPARTICLES BIOSENSOR NOAB IMMUNOASSAY INC. (CA) 1998-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091256-A1 Azepine compounds AZI2, ARL1, APOL1 NPC1 4354/4885RAB9A 980/4885KDM4E 1359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.