Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999141 | 0.98 | THRA (0.46) | THRATHRBALOX5PTGS2LIPG | |
| Water SCHEMBL27918093 | 0.97 | THRA (0.45) | THRATHRBALOX5PTGS2LIPG | |
| Water SCHEMBL27610759 | 0.95 | THRA (0.44) | THRATHRBALOX5PTGS2LIPG | |
| SCHEMBL27955151 | 0.94 | THRA (0.46) | THRATHRBALOX5PTGS2LIPG | |
| Hydrogen Sulfide SCHEMBL4610063 | 0.94 | THRA (0.52) | THRATHRBALOX5PTGS2LIPG | |
| Hydrogen Sulfide SCHEMBL9821128 | 0.93 | THRA (0.51) | THRATHRBALOX5PTGS2LIPG | |
| SCHEMBL1001010 | 0.93 | THRA (0.53) | THRATHRBALOX5PTGS2LIPG | |
| SCHEMBL3929117 | 0.93 | THRA (0.53) | THRATHRBALOX5PTGS2LIPG | |
| SCHEMBL4980580 | 0.93 | THRA (0.53) | THRATHRBALOX5PTGS2LIPG | |
| SCHEMBL10625276 | 0.91 | THRA (0.52) | THRATHRBALOX5PTGS2LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979449-A1 | GREASE COMPOSITION | Shell Internationale Research Maatschappij B.V. (NL) | 2008-10-15 | — | — | EP | disclosed |
| US-20070207934-A1 | GREASE COMPOSITION | SHELL OIL COMPANY | 2007-09-06 | — | — | US | disclosed |
| WO-2007085643-A1 | GREASE COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2007-08-02 | — | — | WO | disclosed |
| EP-1046700-A2 | Grease composition for constant velocity joint | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 2000-10-25 | — | — | EP | disclosed |