Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL6067574 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Terephthalic Acid SCHEMBL4605264 | 0.98 | TSHR (0.57) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Terephthalic Acid SCHEMBL4605471 | 0.93 | TSHR (0.52) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Benzoic Acid SCHEMBL28132510 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2ALDH1A1DAO | |
| Benzoic Acid SCHEMBL14890341 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2ALDH1A1DAO | |
| Terephthalic Acid SCHEMBL4625730 | 0.83 | TSHR (0.46) | TSHRTP53SRD5A2ALDH1A1CA1 | |
| Terephthalic Acid SCHEMBL7629401 | 0.83 | KMT2A (0.45) | TSHRTP53SRD5A2CA1CA2 | |
| Isophthalic Acid SCHEMBL4624459 | 0.82 | CA12 (0.52) | TSHRTP53CA1CA2CA12 | |
| Isophthalic Acid SCHEMBL8125692 | 0.82 | CA12 (0.52) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL332989 | 0.81 | TSHR (0.71) | TSHRTP53SRD5A2ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250297096-A1 | METHOD FOR PRODUCING POLYESTER FILM USING RECYCLED POLYESTER RESIN, AND POLYESTER FILM | TOYOBO CO., LTD (JP) | 2025-09-25 | — | — | US | disclosed |
| EP-4502061-A1 | METHOD FOR PRODUCING POLYESTER FILM USING RECYCLED POLYESTER RESIN, AND POLYESTER FILM | TOYOBO CO., LTD. (JP) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023182131-A1 | METHOD FOR PRODUCING POLYESTER FILM USING RECYCLED POLYESTER RESIN, AND POLYESTER FILM | 東洋紡株式会社 | 2023-09-28 | — | — | WO | disclosed |
| EP-1976903-A2 | METHODS FOR POLYMERIZING MACROCYCLIC POLYESTER OLIGOMERS USING CATALYST PROMOTERS | Cyclics Corporation (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1550513-B1 | Wood substrate comprising an Ultraviolet radiation cured powder coatings | ROHM & HAAS (US) | 2008-08-06 | — | — | EP | disclosed |
| US-7364795-B2 | Ultraviolet radiation cured powder coatings for stained wood | ROHM AND HAAS COMPANY (US) | 2008-04-29 | — | — | US | disclosed |
| EP-1910443-A2 | MACROCYCLIC POLYESTER OLIGOMERS AS CARRIERS AND/OR FLOW MODIFIER ADDITIVES FOR THERMOPLASTICS | Cyclics Corporation (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007117338-A2 | METHODS FOR POLYMERIZING MACROCYCLIC POLYESTER OLIGOMERS USING CATALYST PROMOTERS | CYCLICS CORPORATION (US) | 2007-10-18 | — | — | WO | disclosed |
| US-20070216067-A1 | Macrocyclic polyester oligomers as carriers and/or flow modifier additives for thermoplastics | CYCLICS CORPORATION (US) | 2007-09-20 | — | — | US | disclosed |
| US-7256241-B2 | Methods for polymerizing macrocyclic polyester oligomers using catalyst promoters | CYCLICS CORPORATION (US) | 2007-08-14 | — | — | US | disclosed |
| US-20050136277-A1 | Ultraviolet radiation cured powder coatings for stained wood | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2005-06-23 | — | — | US | disclosed |
| US-6890997-B2 | Powder coating of free radical curable epoxy resin and another free radical curable resin | ROHM AND HAAS COMPANY (US) | 2005-05-10 | — | — | US | disclosed |
| US-20040225058-A1 | Intimate physical mixtures containing macrocyclic polyester oligomer and filler | Goodwin Procter LLP | 2004-11-11 | — | — | US | disclosed |
| US-6777027-B2 | BLEND OF CATIONIC CURABLE RESIN, CATIONIC PHOTOINITIATOR, FREE RADICAL CURABLE RESIN, FREE RADICAL PHOTOINITIATOR; FUSING WITH HEAT AND CURING | ROHM AND HAAS COMPANY | 2004-08-17 | — | — | US | disclosed |
| EP-1408095-A1 | Free radical cured coating powders for low gloss powder coatings | Rohm and Haas (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20040068027-A1 | Free radical cured coating powders for smooth, low gloss powder coatings | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2004-04-08 | — | — | US | disclosed |
| US-20040067304-A1 | Blend of a free radical curable resin, a cationic curable resin, a free radical photoinitiator and a cationic photoinitiator | ROHM AND HAAS COMPANY | 2004-04-08 | — | — | US | disclosed |
| US-20020198331-A1 | POLYESTER RESIN COMPOSITION AND A BOTTLE THEREFROM | NISHIHARA SHUN-ICHI (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-0926197-A1 | POLYESTER RESIN COMPOSITION AND BOTTLE PRODUCED FROM THE RESIN COMPOSITION | MITSUBISHI PLASTICS INC. (JP) | 1999-06-30 | — | — | EP | disclosed |
| US-4140644-A | DIMETHYL-1,3-PROPANEDIOL/2,2-/, DIETHYLENE GLYCOL AND TEREPHTHALIC ACID | EASTMAN KODAK COMPANY (US) | 1979-02-20 | — | — | US | disclosed |