Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837907 | 0.76 | — | — | |
| SCHEMBL8289645 | 0.72 | HTR5A (0.36) | PER2CRY1CRY2HTR5A | |
| SCHEMBL6753128 | 0.71 | — | — | |
| SCHEMBL13611726 | 0.71 | PER2 (0.44) | PER2CRY1CRY2HTR5A | |
| SCHEMBL8781639 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL12477923 | 0.67 | HTR5A (0.36) | PER2CRY1CRY2HTR5A | |
| SCHEMBL11936466 | 0.64 | PER2 (0.40) | PER2CRY1CRY2 | |
| SCHEMBL791484 | 0.62 | — | — | |
| SCHEMBL10908865 | 0.61 | PER2 (0.37) | PER2CRY1CRY2 | |
| SCHEMBL8875557 | 0.61 | GNAO1 (0.36) | PER2CRY1CRY2HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948190-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051810-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2007-05-10 | — | — | WO | disclosed |