SCHEMBL4609249

SCHEMBL4609249

NCC(O)c1cccc(N)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.59
TDP1 Q9NUW8 5/20 0.53
BLM P54132 5/20 0.53
RECQL P46063 4/20 0.53
KDM4E B2RXH2 4/20 0.53
APEX1 P27695 3/20 0.53
TAAR1 Q96RJ0 3/20 0.53
MAPT P10636 3/20 0.53
HPGD P15428 2/20 0.53
CYP3A4 P08684 2/20 0.53
LMNA P02545 2/20 0.53
MAPK1 P28482 2/20 0.53
ADRB2 P07550 2/20 0.53
ADRB1 P08588 2/20 0.53
ADRA2A P08913 2/20 0.53
ADRA2B P18089 2/20 0.53
ADRA2C P18825 2/20 0.53
ADRA1D P25100 2/20 0.53
MEN1 O00255 1/20 0.53
ADORA3 P0DMS8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7146456 1.00 PNMT (0.59) PNMTTDP1BLMRECQLKDM4E
Sulfuric Acid SCHEMBL2987326 0.91 PNMT (0.51) PNMTTDP1BLMRECQLKDM4E
SCHEMBL13323806 0.83 CPN1 (0.46) PNMTTDP1BLMRECQLKDM4E
SCHEMBL2238144 0.83 CPN1 (0.49) PNMTTDP1BLMRECQLKDM4E
SCHEMBL9152377 0.83 CPN1 (0.49) PNMTTDP1BLMRECQLKDM4E
Norfenefrine SCHEMBL1797532 0.81 HIF1A (0.59) PNMTTDP1BLMRECQLKDM4E
Norfenefrine SCHEMBL153494 0.81 HIF1A (0.59) PNMTTDP1BLMRECQLKDM4E
SCHEMBL14530792 0.81 CPN1 (0.47) PNMTTDP1BLMRECQLKDM4E
Norfenefrine SCHEMBL15485360 0.81 HIF1A (0.59) PNMTTDP1BLMRECQLKDM4E
Norfenefrine SCHEMBL9639702 0.81 HIF1A (0.59) PNMTTDP1BLMRECQLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333522-A Green synthesis method of 2, 5-diamino phenethyl alcohol 池州方达科技有限公司 2020-06-26 CN claimed
EP-1660022-B1 AGENT FOR COLOURING KERATIN FIBRES HFC PRESTIGE INT HOLDING SWITZERLAND S A R L (CH) 2017-04-12 EP claimed
WO-2007093954-A1 DYE-CONTAINING PELLETS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 2007-08-23 WO claimed
EP-1820487-A1 Dye-containing pellets and their use Wella Aktiengesellschaft (DE) 2007-08-22 EP claimed
US-20060162097-A1 Dye-containing pellets for dyeing keratin fibres HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2006-07-27 US claimed
EP-1670423-A1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2006-06-21 EP claimed
EP-1660022-A2 AGENT FOR COLOURING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2006-05-31 EP claimed
WO-2005044208-A1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2005-05-19 WO claimed
WO-2005032502-A2 AGENT FOR COLOURING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2005-04-14 WO claimed
US-6800097-B2 FOR DYEING KERATIN FIBERS; HAIR DYES WELLA AKTIENGESELLSCHAFT (DE) 2004-10-05 US claimed
US-20030070241-A1 Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2003-04-17 US claimed
EP-0252351-B1 5-ALKOXY-2,4-DIAMINO-ALKYLBENZENES AND HAIR DYES CONTAINING SAME Wella Aktiengesellschaft (DE) 1990-09-12 EP claimed
EP-0252351-A1 5-Alkoxy-2,4-diamino-alkylbenzenes and hair dyes containing same Wella Aktiengesellschaft (DE) 1988-01-13 EP claimed
EP-1660022-B1 AGENT FOR COLOURING KERATIN FIBRES HFC PRESTIGE INT HOLDING SWITZERLAND S A R L (CH) 2017-04-12 EP disclosed
EP-1771226-B2 MULTICOMPONENT KIT AND METHOD FOR DYEING KERATIN FIBRES Wella GmbH (DE) 2016-03-09 EP disclosed
CN-101001600-B Multicomponent kit and method for dyeing keratin fibers WELLA AG 2013-01-02 CN disclosed
EP-0226072-B1 OXIDATION DYE CONTAINING 4-AMINO-2-AMINOMETHYL PHENOL Wella Aktiengesellschaft (DE) 1991-04-10 EP disclosed
US-4797130-A DYE DEVELOPERS GOOD FOR RED COLORING WELLA AKTIENGESELLSCHAFT (DE) 1989-01-10 US disclosed
EP-0226072-A1 Oxidation dye containing 4-amino-2-aminomethyl phenol Wella Aktiengesellschaft (DE) 1987-06-24 EP disclosed
WO-1987003475-A2 OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1987-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030070241-A1 Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same DDT, ALDH7A1, DDC PNMT 821/4885TDP1 779/4885BLM 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.