Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161241 | 0.91 | OPRM1 (0.58) | CYP2A6OPRM1P2RX3GAAL3MBTL1 | |
| SCHEMBL4597520 | 0.85 | OPRM1 (0.52) | OPRM1P2RX3GAAL3MBTL1EGLN1 | |
| SCHEMBL12775734 | 0.84 | OPRM1 (0.49) | CYP2A6OPRM1P2RX3GAAL3MBTL1 | |
| SCHEMBL19362952 | 0.81 | KDM4E (0.59) | P2RX3GAAL3MBTL1EGLN1KDM4E | |
| SCHEMBL15604704 | 0.80 | CYP2A6 (0.76) | CYP2A6KDM4ERAB9APGRCYP19A1 | |
| SCHEMBL14349927 | 0.80 | P2RX3 (0.48) | P2RX3L3MBTL1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL27368615 | 0.80 | OPRM1 (0.46) | OPRM1P2RX3KDM4EMAP4K4RAB9A | |
| SCHEMBL4598488 | 0.80 | KDM4E (0.50) | CYP2A6OPRM1P2RX3GAAKDM4E | |
| SCHEMBL12967186 | 0.80 | MEN1 (0.58) | P2RX3L3MBTL1EGLN1KDM4ERAB9A | |
| SCHEMBL12844619 | 0.79 | GRN (0.47) | OPRM1L3MBTL1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |