Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686894 | 0.86 | TSHR (0.42) | ALDH1A1TDP1TSHRNPBWR1CYP3A4 | |
| SCHEMBL4609725 | 0.75 | TSHR (0.39) | ALDH1A1TDP1TSHRCYP3A4NPSR1 | |
| SCHEMBL3689847 | 0.73 | IDO1 (0.31) | AGPAT2 | |
| SCHEMBL15292830 | 0.71 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRMCL1NPBWR1 | |
| SCHEMBL16573977 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMCL1NPBWR1 | |
| SCHEMBL15063901 | 0.70 | HTT (0.53) | ALDH1A1TDP1TSHRCYP3A4KMT2A | |
| SCHEMBL20383160 | 0.67 | CYP3A4 (0.56) | ALDH1A1CYP3A4AGPAT2LMNAMAPT | |
| SCHEMBL10770281 | 0.67 | HSD17B10 (0.38) | ALDH1A1TDP1TSHRMCL1CYP3A4 | |
| SCHEMBL3689183 | 0.65 | PTPRC (0.36) | ALDH1A1TDP1TSHRCYP3A4KMT2A | |
| SCHEMBL4608374 | 0.65 | VCAM1 (0.37) | ALDH1A1TDP1CYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |