D-Limonene

D-Limonene

SCHEMBL4609927

C=C(C)[C@H]1CC=C(C)CC1.CC1=CCC(C(C)C)CC1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.75
ALOX15 P16050 4/20 0.47
ALDH1A1 P00352 3/20 0.47
CYP1B1 Q16678 1/20 0.47
TSHR P16473 4/20 0.46
TRPA1 O75762 1/20 0.46
TP53 P04637 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CNR1 P21554 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 2/20 0.36
RAB9A P51151 1/20 0.33
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Limonene SCHEMBL27762454 0.87 LMNA (0.86) LMNAALOX15ALDH1A1CYP1B1TSHR
D-Limonene SCHEMBL22013 0.87 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
D-Limonene SCHEMBL3988306 0.87 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL233098 0.87 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL1871533 0.87 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL8829 0.87 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
D-Limonene SCHEMBL787931 0.87 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL797520 0.87 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL1164294 0.87 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL9804040 0.85 LMNA (0.96) LMNAALOX15ALDH1A1CYP1B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235768-B2 HYDROCARBONACEOUS COMPOSITION CONTAINING ODOR SUPPRESSANT RONYAK ALAN JEFFREY (US) 2008-07-30 EP disclosed
EP-1235768-B1 HYDROCARBONACEOUS COMPOSITION CONTAINING ODOR SUPPRESSANT RONYAK ALAN JEFFREY (US) 2005-03-16 EP disclosed
EP-1235768-A4 HYDROCARBONACEOUS COMPOSITION CONTAINING ODOR SUPPRESSANT RONYAK ALAN JEFFREY (US) 2003-01-08 EP disclosed
US-6461421-B1 ALDEHYDE, KETONE, ESTER RONYAK ALAN JEFFREY (US) 2002-10-08 US disclosed
EP-1235768-A1 HYDROCARBONACEOUS COMPOSITION CONTAINING ODOR SUPPRESSANT Ronyak, Alan Jeffrey (US) 2002-09-04 EP disclosed
WO-2001036354-A1 HYDROCARBONACEOUS COMPOSITION CONTAINING ODOR SUPPRESSANT RONYAK ALAN JEFFREY (US) 2001-05-25 WO disclosed