Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PRKCB | P05771 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | PRKCH | P24723 | 2/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676643 | 0.94 | ALDH1A1 (0.65) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| 2-Hydroxybenzoic Acid Hexyl Ester SCHEMBL29085497 | 0.85 | ALDH1A1 (0.70) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| Diethylamine SCHEMBL3024754 | 0.83 | ALDH1A1 (0.68) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL28229286 | 0.83 | ALDH1A1 (0.71) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| Benzophenone SCHEMBL27409790 | 0.81 | ALDH1A1 (0.82) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL27802407 | 0.81 | ALDH1A1 (0.71) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL818473 | 0.80 | ALDH1A1 (0.79) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL820186 | 0.80 | ALDH1A1 (0.79) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL10482944 | 0.80 | ALDH1A1 (0.79) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL1790206 | 0.80 | ALDH1A1 (0.79) | TSHRALDH1A1LMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119072503-A | Polyolefin, plasticizer for electronic material, cosmetic base material, cosmetic, and lubricant | 日油株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-118748937-A | Water-in-oil type sunscreen cosmetic | 株式会社资生堂 | 2024-10-08 | — | — | CN | disclosed |
| CN-111743811-B | Method and skin care system for reducing sun-induced skin effects on skin | 宝洁公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115151575-B | Galactomannan decomposition product | 太阳化学株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-116528824-A | Composition comprising an ultraviolet filter and one or more (bio) -alkanediols | 西姆莱斯股份公司 | 2023-08-01 | — | — | CN | disclosed |
| EP-1977730-A1 | SUNSCREEN COSMETICS | SHISEIDO COMPANY, LTD. (JP) | 2008-10-08 | — | — | EP | disclosed |