Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.79 |
| ▸ | TSHR | P16473 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | ACP1 | P24666 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818473 | 1.00 | ALDH1A1 (0.79) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL1790206 | 1.00 | ALDH1A1 (0.79) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL10482944 | 1.00 | ALDH1A1 (0.79) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL18473273 | 0.98 | TSHR (0.79) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Benzophenone SCHEMBL27409790 | 0.95 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL818749 | 0.94 | TSHR (0.78) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11985705 | 0.92 | ALDH1A1 (0.65) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11985738 | 0.92 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28231067 | 0.92 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28229286 | 0.92 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200270469-A1 | ACTIVE-ENERGY-RAY-POLYMERIZABLE INITIATOR, ACTIVE-ENERGY-RAY-POLYMERIZABLE COMPOSITION, ACTIVE-ENERGY-RAY-POLYMERIZABLE INK, INK STORAGE CONTAINER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| US-9580571-B2 | Aromatic acylation with cyclic anhydride for plasticizer production | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2017-02-28 | — | — | US | disclosed |
| US-9512296-B2 | Aromatic acylation with cyclic anhydride for plasticizer production | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-12-06 | — | — | US | disclosed |
| US-20140100383-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-04-10 | — | — | US | disclosed |
| US-20140100384-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-04-10 | — | — | US | disclosed |
| US-8604114-B2 | Aromatic acylation with cyclic anhydride for plasticizer production | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-12-10 | — | — | US | disclosed |
| US-20110160371-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | EXXONMOBILE RESEARCH AND ENGINEERING COMPANY (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160371-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | ACAD11, ACOT7, ACOX3 | ALDH1A1 312/4885TSHR 3934/4885LMNA 4020/4885 |
| US-20140100383-A1 | AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION | ACAD11, ACOT7, ACOX3 | ALDH1A1 312/4885TSHR 3934/4885LMNA 4020/4885 |
| US-20200270469-A1 | ACTIVE-ENERGY-RAY-POLYMERIZABLE INITIATOR, ACTIVE-ENERGY-RAY-POLYMERIZABLE COMPOSITION, ACTIVE-ENERGY-RAY-POLYMERIZABLE INK, INK STORAGE CONTAINER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS | ILK, NAP1L4, ORC3 | ALDH1A1 1527/4885TSHR 4775/4885LMNA 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.