SCHEMBL4610100

SCHEMBL4610100

CNS(=O)(=O)c1cc(OC)c(N)cc1OC

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.66
L3MBTL1 Q9Y468 3/20 0.56
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP13 P45452 1/20 0.45
KDM4E B2RXH2 3/20 0.44
GAA P10253 3/20 0.44
ALDH1A1 P00352 2/20 0.44
F2 P00734 2/20 0.43
PRSS1 P07477 2/20 0.43
PRSS2 P07478 2/20 0.43
PRSS3 P35030 2/20 0.43
POLB P06746 2/20 0.41
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
S100B P04271 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777795 0.86 L3MBTL1 (0.53) PKML3MBTL1CA1CA2MMP1
SCHEMBL2914907 0.86 PKM (0.53) PKML3MBTL1CA1CA2MMP1
SCHEMBL31213823 0.86 PKM (0.53) PKML3MBTL1CA1CA2MMP1
SCHEMBL9646206 0.85 PKM (0.60) PKML3MBTL1CA1CA2MMP1
SCHEMBL10810880 0.85 GAA (0.53) PKML3MBTL1CA1CA2MMP1
SCHEMBL9647904 0.83 L3MBTL1 (0.50) PKML3MBTL1CA1CA2MMP1
SCHEMBL12004047 0.81 L3MBTL1 (0.47) PKML3MBTL1CA1CA2MMP1
SCHEMBL8639896 0.80 PKM (0.58) PKML3MBTL1CA1CA2MMP1
SCHEMBL8777777 0.79 PKM (1.00) PKML3MBTL1CA1CA2MMP1
SCHEMBL30068292 0.79 PKM (1.00) PKML3MBTL1CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
EP-4692249-A1 COLORING AGENT, COLORING COMPOSITION, AND METHOD FOR PRODUCING COLORING AGENT Artience Co., Ltd. (JP) 2026-02-11 EP disclosed
WO-2024204597-A1 COLORING AGENT, COLORING COMPOSITION, AND METHOD FOR PRODUCING COLORING AGENT artience株式会社 2024-10-03 WO disclosed
EP-1417264-B1 NOVEL AZO PIGMENTS CLARIANT PRODUKTE DEUTSCHLAND (DE) 2008-10-15 EP disclosed
CN-100381503-C Azo pigment formulations for packaging gravure and flexographic printing CLARIANT GMBH (DE) 2008-04-16 CN disclosed
US-7318863-B2 Azo pigment preparations for packaging gravure and flexographic printing CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2008-01-15 US disclosed
US-7309389-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2007-12-18 US disclosed
US-20070213516-A1 Process For Producing High-Purity Azo Dyes HOELLEIN VOLKER 2007-09-13 US disclosed
US-20070204762-A1 Azo Pigment Preparations for Packaging Gravure and Flexographic Printing CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-09-06 US disclosed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
US-4156617-A Process for preparing organic pigments of high tinctorial strength and grain softness HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-29 US disclosed
US-4150019-A COLORFAST, HEAT RESISTANT, MIGRATION HOECHST AKTIENGESELLSCHAFT (DE) 1979-04-17 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed