SCHEMBL2914907

SCHEMBL2914907

CNS(=O)(=O)c1cc(OC)c(N)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.49
LMNA P02545 2/20 0.45
HTT P42858 2/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
KMT2A Q03164 2/20 0.42
F2 P00734 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
GAA P10253 4/20 0.40
POLB P06746 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31213823 1.00 PKM (0.53) PKML3MBTL1LMNAHTTCA1
SCHEMBL4610100 0.86 PKM (0.66) PKML3MBTL1CA1CA2MMP1
SCHEMBL10810880 0.82 GAA (0.53) PKML3MBTL1LMNACA1CA2
SCHEMBL8644184 0.81 PKM (0.47) PKML3MBTL1LMNAHTTCA1
SCHEMBL11313098 0.81 PKM (0.58) PKML3MBTL1HTTCA1CA2
SCHEMBL7785291 0.81 PKM (0.73) PKML3MBTL1HTTCA1CA2
SCHEMBL29776125 0.81 PKM (0.73) PKML3MBTL1HTTCA1CA2
SCHEMBL27580766 0.81 PKM (0.50) PKML3MBTL1LMNAHTTCA1
SCHEMBL8777795 0.80 L3MBTL1 (0.53) PKML3MBTL1LMNACA1CA2
SCHEMBL8497634 0.79 PKM (0.56) PKML3MBTL1LMNAHTTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479510-B Preparation method of C.I. pigment red 185 绍兴上虞新利化工有限公司 2023-12-08 CN claimed
CN-114479510-A Preparation method of C.I. pigment red 185 绍兴上虞新利化工有限公司 2022-05-13 CN claimed
EP-2121850-B1 NEW CRYSTAL PHASE OF A BENZIMIDAZOLONE AZO PIGMENT BASF SE (DE) 2010-09-01 EP claimed
US-20100104966-A1 CRYSTAL PHASE OF A BENZIMIDAZOLONE AZO PIGMENT CIBA CORPORATION (US) 2010-04-29 US claimed
EP-2121850-A1 NEW CRYSTAL PHASE OF A BENZIMIDAZOLONE AZO PIGMENT BASF SE (DE) 2009-11-25 EP claimed
WO-2008090058-A1 NEW CRYSTAL PHASE OF A BENZIMIDAZOLONE AZO PIGMENT BASF SE (CH) 2008-07-31 WO claimed
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
CN-114479510-B Preparation method of C.I. pigment red 185 绍兴上虞新利化工有限公司 2023-12-08 CN disclosed
CN-114479510-B Preparation method of C.I. pigment red 185 绍兴上虞新利化工有限公司 2023-12-08 CN disclosed
CN-114479510-A Preparation method of C.I. pigment red 185 绍兴上虞新利化工有限公司 2022-05-13 CN disclosed
CN-114479510-A Preparation method of C.I. pigment red 185 绍兴上虞新利化工有限公司 2022-05-13 CN disclosed
EP-2121850-B1 NEW CRYSTAL PHASE OF A BENZIMIDAZOLONE AZO PIGMENT BASF SE (DE) 2010-09-01 EP disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
US-4182708-A Process for the preparation of azo pigments by diazotizing in a dipolar aprotic organic solvent and azo pigments obtained therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-08 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104966-A1 CRYSTAL PHASE OF A BENZIMIDAZOLONE AZO PIGMENT UACA, TYR, CRY1 PKM 314/4885L3MBTL1 4507/4885LMNA 1809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.