Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610114 | 1.00 | CYP2D6 (0.48) | CYP2D6SRCNAALAD2LMNAMTOR | |
| SCHEMBL4611571 | 0.89 | ALDH1A1 (0.47) | CYP2D6LMNACYP3A4ALDH1A1HPGD | |
| SCHEMBL4629661 | 0.85 | ATM (0.59) | LMNACYP3A4ALDH1A1KMT2A | |
| SCHEMBL4630138 | 0.82 | MAPT (0.45) | CYP2D6SRCNAALAD2LMNAMTOR | |
| SCHEMBL11828228 | 0.81 | ALDH1A1 (0.55) | CYP2D6SRCNAALAD2LMNAMAPK1 | |
| SCHEMBL19764847 | 0.81 | ALDH1A1 (0.55) | CYP2D6SRCNAALAD2LMNAMAPK1 | |
| SCHEMBL15592754 | 0.81 | ALDH1A1 (0.55) | CYP2D6SRCNAALAD2LMNAMAPK1 | |
| SCHEMBL11671941 | 0.80 | SRC (0.50) | CYP2D6SRCLMNAMTORRAB9A | |
| SCHEMBL7990151 | 0.80 | ALDH1A1 (0.48) | CYP2D6SRCLMNATSHRCYP3A4 | |
| SCHEMBL11341230 | 0.79 | APAF1 (0.53) | CYP2D6SRCLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923544-B1 | METHOD FOR THE SYNTHESIS OF AMINES AND AMINO ACIDS WITH ORGANOBORON DERIVATIVES | UNIV SOUTHERN CALIFORNIA (US) | 2008-10-15 | — | — | EP | disclosed |
| US-6232467-B1 | BIOSYNTHESIS OF AN AMINE WITH KETONE AND BORON COMPOUND; COMPOUNDLIBRARIES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2001-05-15 | — | — | US | disclosed |
| EP-0923544-A4 | METHOD FOR THE SYNTHESIS OF AMINES AND AMINO ACIDS WITH ORGANOBORON DERIVATIVES | UNIV SOUTHERN CALIFORNIA (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0923544-A1 | METHOD FOR THE SYNTHESIS OF AMINES AND AMINO ACIDS WITH ORGANOBORON DERIVATIVES | University of Southern California (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998000398-A1 | METHOD FOR THE SYNTHESIS OF AMINES AND AMINO ACIDS WITH ORGANOBORON DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1998-01-08 | — | — | WO | disclosed |